| Prenatal diagnosis of gastroschisis: development of objective sonographic criteria for predicting outcome. | |
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MedLine Citation:
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PMID: 8416461 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To determine which sonographic findings predict intestinal damage in fetuses with gastroschisis, and to develop objective criteria that may be useful in selecting candidates for preterm delivery. METHODS: Twenty-four consecutive fetuses at two perinatal centers were assessed retrospectively or prospectively. Maternal, perinatal, and sonographic data were recorded and correlated with postnatal outcome. RESULTS: Bowel diameter of at least 18 mm was associated with a significantly longer time to oral feeding and with significantly greater need for bowel resection. When gestational age was plotted against bowel diameter, a threshold curve was generated, above which all patients had prolonged hypoperistalsis and below which only 30% had prolonged hypoperistalsis. Two infants were delivered at 33 weeks' gestation, both of whom had complications potentially related to prematurity. Only one of 22 patients who delivered later than 33 weeks had similar complications. CONCLUSIONS: Bowel dilatation may be a marker of prenatal bowel damage in fetuses with gastroschisis, especially when it presents late in gestation. Prenatal sonography may be useful in selecting appropriate fetuses for preterm delivery. |
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Authors:
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J C Langer; J Khanna; C Caco; E H Dykes; K H Nicolaides |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 81 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 1993 Jan |
Date Detail:
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Created Date: 1993-01-21 Completed Date: 1993-01-21 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 53-6 Citation Subset: AIM; IM |
Affiliation:
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Department of Surgery, McMaster University, Hamilton, Canada. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abdominal Muscles
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abnormalities* Congenital Abnormalities / pathology, physiopathology, ultrasonography Eating Female Fetal Diseases / ultrasonography* Gastrointestinal Motility Humans Intestines / pathology, surgery Pregnancy Prognosis Prospective Studies Retrospective Studies Ultrasonography, Prenatal* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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