Document Detail

Prenatal diagnosis of gastroschisis: development of objective sonographic criteria for predicting outcome.
MedLine Citation:
PMID:  8416461     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine which sonographic findings predict intestinal damage in fetuses with gastroschisis, and to develop objective criteria that may be useful in selecting candidates for preterm delivery. METHODS: Twenty-four consecutive fetuses at two perinatal centers were assessed retrospectively or prospectively. Maternal, perinatal, and sonographic data were recorded and correlated with postnatal outcome. RESULTS: Bowel diameter of at least 18 mm was associated with a significantly longer time to oral feeding and with significantly greater need for bowel resection. When gestational age was plotted against bowel diameter, a threshold curve was generated, above which all patients had prolonged hypoperistalsis and below which only 30% had prolonged hypoperistalsis. Two infants were delivered at 33 weeks' gestation, both of whom had complications potentially related to prematurity. Only one of 22 patients who delivered later than 33 weeks had similar complications. CONCLUSIONS: Bowel dilatation may be a marker of prenatal bowel damage in fetuses with gastroschisis, especially when it presents late in gestation. Prenatal sonography may be useful in selecting appropriate fetuses for preterm delivery.
J C Langer; J Khanna; C Caco; E H Dykes; K H Nicolaides
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  81     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1993 Jan 
Date Detail:
Created Date:  1993-01-21     Completed Date:  1993-01-21     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  53-6     Citation Subset:  AIM; IM    
Department of Surgery, McMaster University, Hamilton, Canada.
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MeSH Terms
Abdominal Muscles / abnormalities*
Congenital Abnormalities / pathology,  physiopathology,  ultrasonography
Fetal Diseases / ultrasonography*
Gastrointestinal Motility
Intestines / pathology,  surgery
Prospective Studies
Retrospective Studies
Ultrasonography, Prenatal*

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