| Prenatal diagnosis of the fragile X using thymidine induction. | |
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MedLine Citation:
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PMID: 2954037 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Eleven pregnancies in ten patients at risk for the fragile X were monitored by amniocentesis or chorion villus biopsy and induction of the fragile site using thymidine, methotrexate and FUdR. Three female fetuses and one male fetus were found to have the fragile X. The results obtained using thymidine induction were superior to those using methotrexate induction and probably better than those obtained using FUdR induction. |
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Authors:
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G R Sutherland; E Baker; S Purvis-Smith; A Hockey; E Krumins; S Z Eichenbaum |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Prenatal diagnosis Volume: 7 ISSN: 0197-3851 ISO Abbreviation: Prenat. Diagn. Publication Date: 1987 Mar |
Date Detail:
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Created Date: 1987-06-30 Completed Date: 1987-06-30 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8106540 Medline TA: Prenat Diagn Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 197-202 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Amniocentesis Australia Chorionic Villi* Female Floxuridine / diagnostic use Fragile X Syndrome / diagnosis*, epidemiology Humans Male Methotrexate / diagnostic use Pregnancy Prenatal Diagnosis* Sex Chromosome Aberrations / diagnosis* Thymidine / diagnostic use |
| Chemical | |
Reg. No./Substance:
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50-89-5/Thymidine; 50-91-9/Floxuridine; 59-05-2/Methotrexate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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