| Prenatal diagnosis of anoxic cerebral lesions caused by profound fetal anemia secondary to maternal red blood cell alloimmunization. | |
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MedLine Citation:
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PMID: 18669757 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The long-term neurological prognosis of severe fetal anemia is usually considered favorable, especially when fetal hydrops regresses after successful in utero transfusion. CASES: We report two cases of prenatally diagnosed fetal cerebral anoxic lesions associated with severe fetal anemia despite appropriate and successful treatment by in utero transfusion. The two pregnancies were terminated. CONCLUSION: Profound fetal anemia may cause anoxic lesions of the fetal brain that may be diagnosed prenatally. If new onset ventriculomegaly is observed on ultrasonography after in utero transfusion for severe fetal anemia, anoxic lesions could be suspected. |
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Authors:
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Bruno Carbonne; Amélie Nguyen; Evelyne Cynober; Vanina Castaigne; Anne Cortey; Yves Brossard |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 112 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 2008 Aug |
Date Detail:
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Created Date: 2008-08-01 Completed Date: 2008-09-09 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 442-4 Citation Subset: AIM; IM |
Affiliation:
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Centre National de Référence en Hémobiologie Périnatale, Hôpital Saint-Antoine, Paris, France. bruno.carbonne@sat.aphp.fr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anemia / blood, immunology*, ultrasonography Female Fetal Diseases / blood, immunology*, ultrasonography Humans Hypoxia, Brain / blood, immunology*, ultrasonography Kell Blood-Group System / immunology* Pregnancy Rh Isoimmunization / complications*, ultrasonography Ultrasonography, Prenatal |
| Chemical | |
Reg. No./Substance:
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0/Kell Blood-Group System |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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