Document Detail


Prenatal detection of monosomy 18p and trisomy 18q mosaicism with unexpected fetal phenotype.
MedLine Citation:
PMID:  3723556     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A mosaic karyotype 46,XX,del(18)(p11)/46,XX,-18,+?i(18q) was found in cultured amniotic cells. Fetal blood sampling confirmed the presence of both cell lines. The pregnancy was terminated and the two cell lines were demonstrated in varying proportions in the fetal tissues. The few abnormal features seen in the fetus may represent a mild expression of the 18p-- phenotype inhibiting the effects of the trisomy 18q.
Authors:
S D Sutton; M A Ridler
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of medical genetics     Volume:  23     ISSN:  0022-2593     ISO Abbreviation:  J. Med. Genet.     Publication Date:  1986 Jun 
Date Detail:
Created Date:  1986-07-25     Completed Date:  1986-07-25     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985087R     Medline TA:  J Med Genet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  258-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Abortion, Induced
Adult
Amniotic Fluid / cytology
Chromosome Banding
Chromosome Deletion*
Chromosomes, Human, 16-18*
Female
Humans
Karyotyping
Mosaicism*
Phenotype
Pregnancy
Prenatal Diagnosis*
Trisomy*
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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