| Prenatal cocaine exposure and prematurity: neurodevelopmental growth. | |
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MedLine Citation:
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PMID: 10972249 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The consequences of prematurity and prenatal cocaine exposure on early neurobehavior and physical growth were examined longitudinally in a sample of 20 cocaine-exposed and 20 non-exposed preterm neonates. The magnitude of the difference in physical growth acceleration related to prenatal cocaine exposure increased with increasing birth gestational age, whereas growth rate differences in irritability decreased. In contrast, prenatal cocaine exposure, independent of prematurity, was related to reduced attention skills at 36 weeks conceptional age and increased rates of neurobehavioral change. The effects of prenatal cocaine exposure differed with respect to the degree of prematurity, depending on the nature of the outcome examined, suggesting differing windows of vulnerability for different outcome domains. The usefulness of a developmental growth perspective was demonstrated. |
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Authors:
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K Andrews; D J Francis; M L Riese |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of developmental and behavioral pediatrics : JDBP Volume: 21 ISSN: 0196-206X ISO Abbreviation: J Dev Behav Pediatr Publication Date: 2000 Aug |
Date Detail:
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Created Date: 2001-02-02 Completed Date: 2001-02-02 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8006933 Medline TA: J Dev Behav Pediatr Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 262-70 Citation Subset: IM |
Affiliation:
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Department of Psychiatry, Southern Illinois University School of Medicine, Carbondale, Illinois 62901-6503, USA. kespy@siumed.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Arousal
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drug effects Attention / drug effects Cocaine / adverse effects* Developmental Disabilities / chemically induced*, diagnosis Female Gestational Age Humans Infant, Newborn Infant, Premature, Diseases / chemically induced*, diagnosis Longitudinal Studies Neurologic Examination / drug effects Pregnancy Prenatal Exposure Delayed Effects* Risk Factors |
| Grant Support | |
ID/Acronym/Agency:
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HD-22637/HD/NICHD NIH HHS |
| Chemical | |
Reg. No./Substance:
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50-36-2/Cocaine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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