| Prenatal cocaine exposure and infant cortisol reactivity. | |
| | |
MedLine Citation:
|
PMID: 19467009 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This study examined the effects of prenatal cocaine exposure on infant hypothalamic-pituitary-adrenal axis activity and reactivity at 7 months of infant age. Participants were 168 caregiver-infant dyads (87 cocaine exposed, 81 not cocaine exposed; 47% boys). Maternal behavior, caregiving instability, and infant growth and behavior were assessed, and children's saliva was sampled before, during, and after standardized procedures designed to elicit emotional arousal. Results revealed cocaine-exposed infants had a high amplitude trajectory of cortisol reactivity compared to non-cocaine-exposed infants. Infant gender and caregiving instability moderated this association. The findings support a dual hazard vulnerability model and have implications for evolutionary-developmental theories of individual differences in biological sensitivity to context. |
| | |
Authors:
|
Rina D Eiden; Yvette Veira; Douglas A Granger |
Related Documents
:
|
16498669 - Interaction between maternal smoking and malnutrition in infant risk of gastroschisis. 10910119 - Time budgets of infants for exposure assessment: a methodological study. 1992399 - Brain growth among fetuses exposed to cocaine in utero: asymmetrical growth retardation. 2296489 - Jitteriness in full-term neonates: prevalence and correlates. 15059789 - Maternal atopic disease modifies effects of prenatal risk factors on exhaled nitric oxi... 16761079 - No increased risk of infant hypospadias after maternal use of loratadine in early pregn... 53499 - Pancreatic-islet fibrosis in young infants of diabetic mothers. 12286649 - Britain in europe: international and regional comparisons of fertility levels and trends. 2740699 - Polysomnographic sleep and waking states are similar in subsequent siblings of sids and... |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
|
Title: Child development Volume: 80 ISSN: 1467-8624 ISO Abbreviation: Child Dev Publication Date: 2009 Mar-Apr |
Date Detail:
|
Created Date: 2009-05-26 Completed Date: 2009-09-22 Revised Date: 2012-10-09 |
Medline Journal Info:
|
Nlm Unique ID: 0372725 Medline TA: Child Dev Country: United States |
Other Details:
|
Languages: eng Pagination: 528-43 Citation Subset: IM |
Affiliation:
|
University at Buffalo, State University of New York, USA. eiden@ria.buffalo.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Case-Control Studies Child Development / drug effects* Cocaine / administration & dosage*, toxicity* Female Humans Hydrocortisone / metabolism* Hypothalamo-Hypophyseal System / drug effects, metabolism Infant Male Pituitary-Adrenal System / drug effects, metabolism Pregnancy Prenatal Exposure Delayed Effects* Saliva / chemistry, drug effects |
| Grant Support | |
ID/Acronym/Agency:
|
1R01DA013190/DA/NIDA NIH HHS; R01 DA013190/DA/NIDA NIH HHS; R01 DA013190-07/DA/NIDA NIH HHS |
| Chemical | |
Reg. No./Substance:
|
50-23-7/Hydrocortisone; 50-36-2/Cocaine |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Maternal insightfulness and resolution of the diagnosis are associated with secure attachment in pre...
Next Document: The development of regulatory functions from birth to 5 years: insights from premature infants.