| Prenatal closure of the ductus arteriosus and maternal ingestion of anthocyanins. | |
| | |
MedLine Citation:
|
PMID: 20351708 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Prenatal closure of the ductus arteriosus (DA) is associated with maternal ingestion of cyclooxygenase inhibitors during pregnancy. We report a case of prenatal DA closure after maternal ingestion of MonaVie, a juice blend containing the cyclooxygenase and nitric oxide synthase inhibitors anthocyanins and proanthocyanidins. A G(2)P(0)Ab(1) woman had an uncomplicated first and second trimester and normal 20-week fetal ultrasound. At 37 weeks, she developed polyhydramnios; a fetal echocardiogram showed right atrial and ventricular (RV) enlargement with RV dysfunction. Immediately after birth, there was pulmonary hypertension by echocardiogram with DA closure, severe RV hypertrophy and dysfunction, and marked right-to-left atrial shunting. Improvement occurred over 3 weeks with the neonate tolerating room air and a follow-up echocardiogram showing minimal atrial shunting and improved RV function. This report shows an association between MonaVie ingestion throughout pregnancy and prenatal DA closure resulting in cardiac dysfunction and pulmonary hypertension at birth. |
| | |
Authors:
|
V Kapadia; D Embers; E Wells; M Lemler; C R Rosenfeld |
Related Documents
:
|
23301458 - Reduced maternal selenium levels in pregnant and lactating nigerian women: should routi... 10320278 - The use of pulsatile perfusion during aortic valve replacement in pregnancy. 18716138 - Evaluation of referral indications for fetal echocardiography in beijing. 11094218 - Decompression of fetal cardiac tamponade caused by congenital capillary hemangioma of t... 7031838 - Fluoroimmunoassay of pregnancy zone protein. 18080598 - Neural tube defects in a university teaching hospital in southern nigeria: trends and o... |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Journal of perinatology : official journal of the California Perinatal Association Volume: 30 ISSN: 1476-5543 ISO Abbreviation: J Perinatol Publication Date: 2010 Apr |
Date Detail:
|
Created Date: 2010-03-30 Completed Date: 2010-07-30 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8501884 Medline TA: J Perinatol Country: United States |
Other Details:
|
Languages: eng Pagination: 291-4 Citation Subset: IM |
Affiliation:
|
Division of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Anthocyanins / adverse effects* Dietary Supplements / adverse effects*, analysis Ductus Arteriosus / abnormalities, embryology, ultrasonography* Female Heart Defects, Congenital / chemically induced*, ultrasonography Humans Pregnancy Ultrasonography, Prenatal* |
| Chemical | |
Reg. No./Substance:
|
0/Anthocyanins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The role of endothelial function and its assessment in rheumatoid arthritis.
Next Document: Early and severe indirect hyperbilirubinemia as a manifestation of galactosemia.