| Prenatal alcohol and offspring development: the first fourteen years. | |
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MedLine Citation:
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PMID: 7851285 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This report summarizes findings from a prospective longitudinal study of the effects of prenatal alcohol exposure on a birth cohort of 500 offspring selected from 1,529 consecutive pregnant women in prenatal care by mid-pregnancy at two representative community hospitals. Effects of prenatal alcohol observable on size measures at birth were insignificant after 8 months. Morphometric analysis of facial features identified effects only at the very highest alcohol exposure levels. By contrast, dose-dependent effects on neurobehavioral function from birth to 14 years have been established using partial least squares (PLS) methods jointly analysing multiple measures of both alcohol dose and outcome. Particularly salient effects included problems with attention, speed of information processing, and learning problems, especially arithmetic. |
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Authors:
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A P Streissguth; H M Barr; P D Sampson; F L Bookstein |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Drug and alcohol dependence Volume: 36 ISSN: 0376-8716 ISO Abbreviation: Drug Alcohol Depend Publication Date: 1994 Oct |
Date Detail:
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Created Date: 1995-03-15 Completed Date: 1995-03-15 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7513587 Medline TA: Drug Alcohol Depend Country: IRELAND |
Other Details:
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Languages: eng Pagination: 89-99 Citation Subset: IM |
Affiliation:
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Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle 98195. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Attention Deficit Disorder with Hyperactivity / diagnosis Child Child, Preschool Cohort Studies Dose-Response Relationship, Drug Female Fetal Alcohol Syndrome / diagnosis* Humans Infant Infant, Newborn Learning Disorders / diagnosis Longitudinal Studies Male Neuropsychological Tests Pregnancy Prospective Studies Risk Factors Washington |
| Grant Support | |
ID/Acronym/Agency:
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AA0145501-20/AA/NIAAA NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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