Document Detail


Prenatal alcohol exposure and signs of minor neurological dysfunction at preschool age.
MedLine Citation:
PMID:  10981927     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
High levels of alcohol consumption during pregnancy affect the development of the baby's central nervous system. Pregnant women were interviewed about their alcohol consumption during pregnancy, when they first visited the maternity hospital in Roubaix, France. Of the 698 women interviewed, 156 of their children were investigated at the age of 4 1/2 years with a standardised examination to assess the effects of prenatal alcohol exposure on neurological status. Two scores were calculated: a posture score, which measured items while the child was standing; and a minor neurological signs score. The posture score was not related to prenatal alcohol exposure. Consumption of 21 drinks/week (3 drinks/day) or more during pregnancy was significantly associated with a higher number of minor neurological signs, after controlling for relevant covariables. Although prenatal alcohol exposure was related to a lower General Cognitive Index (GCI), minor neurological signs were associated with prenatal alcohol exposure after controlling for GCI.
Authors:
B Larroque; M Kaminski; P Dehaene; D Subtil; D Querleu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Developmental medicine and child neurology     Volume:  42     ISSN:  0012-1622     ISO Abbreviation:  Dev Med Child Neurol     Publication Date:  2000 Aug 
Date Detail:
Created Date:  2000-09-21     Completed Date:  2000-09-21     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0006761     Medline TA:  Dev Med Child Neurol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  508-14     Citation Subset:  IM    
Affiliation:
Institut National de la Santé et de la Recherche Médicale Unit 149, Villejuif, France. larroque@vjf.inserm.fr
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MeSH Terms
Descriptor/Qualifier:
Adult
Alcohol Drinking / adverse effects*
Child, Preschool
Cognition Disorders / etiology
Developmental Disabilities / etiology*
Female
Humans
Male
Maternal Exposure
Neurologic Examination
Posture
Pregnancy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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