| Prenatal alcohol exposure and offspring growth at 18 months of age: the predictive validity of two measures of drinking. | |
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MedLine Citation:
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PMID: 1789387 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This is an analysis of the effect of prenatal alcohol exposure on growth of the offspring at 18 months of age. In this prospective study, a cohort of women was interviewed at the end of each trimester of pregnancy, at delivery, and at 8 and 18 months. Offspring were examined at each follow-up point. Two drinking scales, average daily volume (ADV) and frequent heavy drinking (FHD), were used to explore the effect of different patterns of drinking. We found significant relationships between both prenatal FHD and ADV and offspring growth at 18 months. A significant and inverse relationship was found between ADV during the second and the third trimesters of pregnancy and weight, height, and head circumference at 18 months. Frequent heavy drinking during all three trimesters predicted a significant decrease in head circumference at 18 months. FHD during the second trimester was significantly related to weight and height at 18 months. Analyses demonstrated that ADV was a better predictor of growth deficits than FHD. |
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Authors:
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N L Day; L Goldschmidt; N Robles; G Richardson; M Cornelius; P Taylor; D Geva; D Stoffer |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Alcoholism, clinical and experimental research Volume: 15 ISSN: 0145-6008 ISO Abbreviation: Alcohol. Clin. Exp. Res. Publication Date: 1991 Dec |
Date Detail:
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Created Date: 1992-03-20 Completed Date: 1992-03-20 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7707242 Medline TA: Alcohol Clin Exp Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 914-8 Citation Subset: IM |
Affiliation:
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University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213-2593. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Alcohol Drinking / adverse effects*, physiopathology Anthropometry Birth Weight / drug effects, physiology Body Height / drug effects*, physiology Body Weight / drug effects*, physiology Cohort Studies Dose-Response Relationship, Drug Ethanol / adverse effects* Female Fetal Alcohol Syndrome / diagnosis, physiopathology* Follow-Up Studies Humans Infant Infant, Newborn Male Pregnancy |
| Grant Support | |
ID/Acronym/Agency:
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AA00115/AA/NIAAA NIH HHS; AA06390/AA/NIAAA NIH HHS; AA06666/AA/NIAAA NIH HHS |
| Chemical | |
Reg. No./Substance:
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64-17-5/Ethanol |
| Comments/Corrections | |
Comment In:
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Alcohol Clin Exp Res. 1991 Dec;15(6):903-4
[PMID:
1789385
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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