Document Detail


Prenatal alcohol exposure and offspring growth at 18 months of age: the predictive validity of two measures of drinking.
MedLine Citation:
PMID:  1789387     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This is an analysis of the effect of prenatal alcohol exposure on growth of the offspring at 18 months of age. In this prospective study, a cohort of women was interviewed at the end of each trimester of pregnancy, at delivery, and at 8 and 18 months. Offspring were examined at each follow-up point. Two drinking scales, average daily volume (ADV) and frequent heavy drinking (FHD), were used to explore the effect of different patterns of drinking. We found significant relationships between both prenatal FHD and ADV and offspring growth at 18 months. A significant and inverse relationship was found between ADV during the second and the third trimesters of pregnancy and weight, height, and head circumference at 18 months. Frequent heavy drinking during all three trimesters predicted a significant decrease in head circumference at 18 months. FHD during the second trimester was significantly related to weight and height at 18 months. Analyses demonstrated that ADV was a better predictor of growth deficits than FHD.
Authors:
N L Day; L Goldschmidt; N Robles; G Richardson; M Cornelius; P Taylor; D Geva; D Stoffer
Related Documents :
14616177 - Fetus at risk: prevalence of alcohol consumption during pregnancy estimated with a simp...
2530447 - Ultrastructural changes in the mouse fetal choroid plexuses following chronic maternal ...
15940677 - Minor malformations characteristic of the retinoic acid embryopathy and other birth out...
17233797 - Systematic review of effects of low-moderate prenatal alcohol exposure on pregnancy out...
17359587 - Is hysteroscopic correction of an incomplete uterine septum justified prior to ivf?
5971007 - Ultrastructure of the carotid body.
Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Alcoholism, clinical and experimental research     Volume:  15     ISSN:  0145-6008     ISO Abbreviation:  Alcohol. Clin. Exp. Res.     Publication Date:  1991 Dec 
Date Detail:
Created Date:  1992-03-20     Completed Date:  1992-03-20     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7707242     Medline TA:  Alcohol Clin Exp Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  914-8     Citation Subset:  IM    
Affiliation:
University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213-2593.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Alcohol Drinking / adverse effects*,  physiopathology
Anthropometry
Birth Weight / drug effects,  physiology
Body Height / drug effects*,  physiology
Body Weight / drug effects*,  physiology
Cohort Studies
Dose-Response Relationship, Drug
Ethanol / adverse effects*
Female
Fetal Alcohol Syndrome / diagnosis,  physiopathology*
Follow-Up Studies
Humans
Infant
Infant, Newborn
Male
Pregnancy
Grant Support
ID/Acronym/Agency:
AA00115/AA/NIAAA NIH HHS; AA06390/AA/NIAAA NIH HHS; AA06666/AA/NIAAA NIH HHS
Chemical
Reg. No./Substance:
64-17-5/Ethanol
Comments/Corrections
Comment In:
Alcohol Clin Exp Res. 1991 Dec;15(6):903-4   [PMID:  1789385 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Prenatal alcohol exposure and preschool physical growth: a longitudinal analysis.
Next Document:  Postnatal growth deficits in prenatal ethanol-exposed mice: characteristics and critical periods.