Document Detail

Prenatal VOC exposure and redecoration are related to wheezing in early infancy.
MedLine Citation:
PMID:  25233103     Owner:  NLM     Status:  Publisher    
OBJECTIVES: The aim of the present study was to evaluate the impact of prenatal exposure on early wheeze and to identify sensitive time windows. Within the LINA birth cohort study data on renovation activities and respiratory outcomes were assessed via questionnaires during pregnancy and at children's age of one. At both timepoints, also indoor VOC concentrations were measured. The associations were studied by logistic regression analysis. Floor covering during pregnancy contributed to an increased risk for physician treated wheeze (adjusted odds ratio OR=5.20, 95% confidence interval 1.8-15.2) during the first 12months after birth in particular in children with an atopic predisposition. Thereby, wall-to-wall-carpets, PVC material, and laminate were the flooring materials which showed the strongest adverse associations. Floor covering was associated with enhanced concentrations of VOCs in the apartments. For the VOCs styrene, ethylbenzene, octane, 1-butanol, tridecane, and o-xylene, a significant association was found to the occurrence of wheezing symptoms. In contrast to pregnancy, exposure during the first 12months after birth showed less detrimental associations. Only the association between wheezing and styrene as well as between wheezing and PVC flooring remained significant for exposure after birth. Redecoration during pregnancy, especially changing floor materials, increases the risk for respiratory diseases in early childhood and should therefore be avoided at least in families with a history of atopic diseases.
Ulrich Franck; Annegret Weller; Stefan W Röder; Gunda Herberth; Kristin M Junge; Tibor Kohajda; Martin von Bergen; Ulrike Rolle-Kampczyk; Ulrike Diez; Michael Borte; Irina Lehmann;
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-9-15
Journal Detail:
Title:  Environment international     Volume:  73C     ISSN:  1873-6750     ISO Abbreviation:  Environ Int     Publication Date:  2014 Sep 
Date Detail:
Created Date:  2014-9-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7807270     Medline TA:  Environ Int     Country:  -    
Other Details:
Languages:  ENG     Pagination:  393-401     Citation Subset:  -    
Copyright Information:
Copyright © 2013. Published by Elsevier Ltd.
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