| Prenatal Exposure to Non-ionizing Radiation: Effects of WiFi Signals on Pregnancy Outcome, Peripheral B-Cell Compartment and Antibody Production. | |
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MedLine Citation:
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PMID: 20874434 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Abstract During embryogenesis, the development of tissues, organs and systems, including the immune system, is particularly susceptible to the effects of noxious agents. We examined the effects of prenatal (in utero) exposure to WiFi signals on pregnancy outcome and the immune B-cell compartment, including antibody production. Sixteen mated (plug-positive) female mice were assigned to each of the following groups: cage control, sham-exposed and microwave-exposed (WiFi signals at 2.45 GHz, whole body, SAR 4 W/kg, 2 h/day, 14 consecutive days starting 5 days after mating). No effects due to exposure to WiFi signals during pregnancy on mating success, number of newborns/mother and body weight at birth were found. Newborn mice were left to grow until 5 or 26 weeks of age, when immunological analyses were performed. No differences due to exposure were found in spleen cell number, B-cell frequency or antibody serum levels. When challenged in vitro with LPS, B cells from all groups produced comparable amounts of IgM and IgG, and proliferated at a similar level. All these findings were consistently observed in the female and male offspring at both juvenile (5 weeks) and adult (26 weeks) ages. Stress-associated effects as well as age- and/or sex-related differences were observed for several parameters. In conclusion, our results do not show any effect on pregnancy outcome or any early or late effects on B-cell differentiation and function due to prenatal exposure to WiFi signals. |
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Authors:
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Manolo Sambucci; Federica Laudisi; Francesca Nasta; Rosanna Pinto; Rossella Lodato; Pierluigi Altavista; Giorgio Alfonso Lovisolo; Carmela Marino; Claudio Pioli |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2010-9-28 |
Journal Detail:
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Title: Radiation research Volume: - ISSN: 1938-5404 ISO Abbreviation: - Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-9-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401245 Medline TA: Radiat Res Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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ENEA (Italian Agency for New Technologies, Energy and Sustainable Economic Development), Unit of Radiation Biology and Human Health, Rome, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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