Document Detail


Premenarchal vulvar ulceration: is chronic irritation a causative factor?
MedLine Citation:
PMID:  19840303     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To study the common features of the young girls with vulvar ulcerations, and to help guide physicians caring for girls with this unusual condition. METHODS: In this retrospective study, ten patients who developed vulvar ulcerations and denied any kind of sexual contact or sexual abuse were identified. Patient information was collated from detailed history, physical, and laboratory examinations including age, menarchal status, type of clothing worn, whether history of oral aphthosis or previous vulvar ulcers had occurred, symptoms at the time of presentation, description of ulcer, laboratory studies including serologies, blood count, erythrocyte sedimentation rate, C-reactive protein, and biopsy results. RESULTS: Despite multiple evaluations, no patient had a specific medical cause identified to account for their vulvar ulcerations. None were diagnosed with Behcet's syndrome. Seven had bilateral vulvar ulcerations, which we attribute to the practice of wearing tightly fitted pants or polyester underwear frequently. No recurrences were documented in 6 months follow-up. CONCLUSION: Girls with vulvar ulcerations who have deny being sexually active should be thoroughly evaluated for infections, Behcet's disease, and other health problems, but, in addition, should be questioned about use of tight-fitting clothing in the perineal area. We hypothesize that chronic irritation because of tight clothing may play a role in causing vulvar ulcerations in this setting.
Authors:
Fatma Bahar Cebesoy; Ozcan Balat; Serhat Inaloz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatric dermatology     Volume:  26     ISSN:  1525-1470     ISO Abbreviation:  Pediatr Dermatol     Publication Date:    2009 Sep-Oct
Date Detail:
Created Date:  2009-10-20     Completed Date:  2010-01-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8406799     Medline TA:  Pediatr Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  514-8     Citation Subset:  IM    
Affiliation:
Obstetric and Gynecology Department, Gaziantep University Faculty of Medicine, Gaziantep, Turkey. fbcebesoy@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Child
Chronic Disease
Clothing*
Female
Follow-Up Studies
Humans
Irritants*
Puberty
Retrospective Studies
Skin Ulcer / etiology*
Vulvar Diseases / etiology*
Chemical
Reg. No./Substance:
0/Irritants

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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