Document Detail


Prematurity and intrauterine growth retardation--double jeopardy?
MedLine Citation:
PMID:  15325532     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Premature infants born with IUGR are at a several-fold increased risk for mortality and major neonatal morbidities, including RDS, BPD, ROP, and NEC. These severe complications of prematurity are intensified by the effect of suboptimal fetal growth. The possible pathophysiologic processes initiated in utero and continuing after birth have been discussed. Recently reported data suggest that IUGR is a risk factor in programming for the later development of cardiovascular diseases, hypertension, and diabetes mellitus in adult life. Experimental research related to the pathophysiology and etiology of these conditions may enable appropriate intervention directed at reducing the excess risk associated with the short- and long-term mortality and morbidity among premature SGA infants.
Authors:
Rivka H Regev; Brian Reichman
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinics in perinatology     Volume:  31     ISSN:  0095-5108     ISO Abbreviation:  Clin Perinatol     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-08-24     Completed Date:  2005-02-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7501306     Medline TA:  Clin Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  453-73     Citation Subset:  IM    
Affiliation:
Neonatal Unit and Neonatal Follow-Up Clinic, Neonatal Department, Meir Hospital, Sapir Medical Center, Kfar Saba 44281, Israel. regevdr@netvision.net.il
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MeSH Terms
Descriptor/Qualifier:
Female
Fetal Growth Retardation / complications*,  mortality,  physiopathology*
Gestational Age
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / mortality,  physiopathology*
Morbidity
Pregnancy
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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