| Prematurity in multiple gestations: identification of patients who are at low risk. | |
| | |
MedLine Citation:
|
PMID: 12066087 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: The purpose of this study was to evaluate a strategy for the identification of patients with multiple gestations who are at low risk for preterm delivery. STUDY DESIGN: A prospective observational study among patients with twin and triplet gestations. At 20 and 24 weeks of gestation, screening for bacterial vaginosis and fetal fibronectin was performed, followed by digital and sonographic assessment of the cervix. The treating physicians were blinded to test results. RESULTS: At the 24-week examination, specificities for delivery at >32 weeks of gestation for digital examination (92.9%), fetal fibronectin level (93.9%), cervical length on sonographic scan (85.1%), and combined fetal fibronectin level and cervical length (81.3%) did not differ statistically. Negative predictive values for these tests were >or=95%. All tests performed better at 24 weeks of gestation than at 20 weeks of gestation. CONCLUSION: At 24 weeks of gestation, a normal digital examination, a negative fetal fibronectin level, a normal cervical length on sonographic scan, or the combination of a negative fetal fibronectin level and a normal cervical length each confer a similarly high likelihood of delivery at >32 weeks of gestation in women with multiple gestations. |
| | |
Authors:
|
Kimberly S McMahon; Mark G Neerhof; Elaine I Haney; Hope A Thomas; Richard K Silver; Alan M Peaceman |
Related Documents
:
|
1354207 - Cervical cerclage in uterine malformations. 2695057 - Cervical incompetence in a pregnancy following a cervical ectopic pregnancy. 12913877 - Prenatal presentation of cervical congenital neuroblastoma. 8855677 - Cervical ectopic pregnancy: a case report. 13677267 - Pregnancy-associated thrombosis. 12623767 - Factors associated with unwanted pregnancy. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: American journal of obstetrics and gynecology Volume: 186 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2002 Jun |
Date Detail:
|
Created Date: 2002-06-14 Completed Date: 2002-07-11 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
|
Languages: eng Pagination: 1137-41 Citation Subset: AIM; IM |
Affiliation:
|
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Northwestern University Medical School, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Cervix Uteri / physiology, ultrasonography Female Fetal Blood Fibronectins / blood Gestational Age Humans Infant, Newborn Infant, Premature* Likelihood Functions Physical Examination Predictive Value of Tests Pregnancy Pregnancy Complications, Infectious / physiopathology Pregnancy, Multiple* Prospective Studies Risk Factors Sensitivity and Specificity Vaginosis, Bacterial / physiopathology |
| Chemical | |
Reg. No./Substance:
|
0/Fibronectins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Procedural risks versus theology: chorionic villus sampling for Orthodox Jews at less than 8 weeks' ...
Next Document: Acceptance of altering the standard 21-day/7-day oral contraceptive regimen to delay menses and redu...