| Premature rupture of membranes at < 25 weeks: a management dilemma. | |
| | |
MedLine Citation:
|
PMID: 8438918 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: A retrospective study was conducted to establish the perinatal and long-term neonatal outcome at 1 year of life (corrected) of pregnancies complicated by premature rupture of membranes before fetal viability. STUDY DESIGN: The outcome of 94 singleton pregnancies admitted from June 1982 to June 1991 with premature rupture of membranes at < 25 weeks' gestation that were managed expectantly were studied. To establish the effect of rupture of membranes, the neonatal outcomes of babies born with birth weights > 500 gm and gestational ages > 24 weeks were compared with those of a similar group of neonates from patients without preterm rupture of membranes and matched by gestational age, birth weight, race, sex, and mode of delivery. The outcome of the surviving neonates at 1 year of life (corrected) was established on the basis of their Bailey mental and psychomotor scores and on the results of neurologic, ophthalmologic, and hearing examinations. RESULTS: The overall incidence of amnionitis was 24%. The median latency period was 10.5 days; in 26% of patients delivery was delayed > 2 weeks. Pulmonary hypoplasia was detected in 5% of patients, and there was no evidence of orthopedic deformities. Survival was achieved in 39 (40%) of neonates; 63% of these survivors were considered to have had normal development at 1 year of life (corrected). CONCLUSION: Premature rupture of membranes at < 25 weeks is associated with a relatively high risk of perinatal mortality and neonatal and long-term morbidity, but a successful outcome can be achieved in about 60% of survivors. |
| | |
Authors:
|
W J Morales; T Talley |
Related Documents
:
|
724168 - Placenta previa. predisposing factors and effects on the fetus and surviving infants. 8653438 - Use of wigglesworth pathophysiological classification for perinatal mortality in malaysia. 19459528 - Perinatal death pattern in the four districts of thailand: findings from the prospectiv... 12562468 - Perinatal mortality in turkey. 7025638 - Effect of antenatal dexamethasone administration on the prevention of respiratory distr... 2929548 - Vaginal "fisting" as a cause of death. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: American journal of obstetrics and gynecology Volume: 168 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 1993 Feb |
Date Detail:
|
Created Date: 1993-03-22 Completed Date: 1993-03-22 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 503-7 Citation Subset: AIM; IM |
Affiliation:
|
Orlando Regional Medical Center, FL. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Birth Weight Female Fetal Membranes, Premature Rupture / mortality, therapy* Gestational Age* Humans Infant Mortality Infant, Newborn Pregnancy Pregnancy Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Immature lecithin/sphingomyelin ratios and neonatal respiratory course.
Next Document: Beneficial effects of the combined use of prenatal corticosteroids and postnatal surfactant on prete...