| Premature fusion of the proximal humeral epiphyses in thalassemia. | |
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MedLine Citation:
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PMID: 6600336 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Premature fusion of the proximal humeral epiphyses with varus deformity is a common and characteristic radiologic finding in thalassemia anemia. A review of 17 cases with bilateral and one case with unilateral involvement, coupled with known anatomic and mechanical factors, suggested an explanation for this phenomenon. Hypertrophied marrow will thin the trabeculae and cortex, perforate the cortex through normal fenestrations, and proliferate subperiosteally. Normal force vectors result in medial humeral compression and ultimately premature fusion. |
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Authors:
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J P Lawson; R C Ablow; H A Pearson |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: AJR. American journal of roentgenology Volume: 140 ISSN: 0361-803X ISO Abbreviation: AJR Am J Roentgenol Publication Date: 1983 Feb |
Date Detail:
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Created Date: 1983-02-14 Completed Date: 1983-02-14 Revised Date: 2008-02-15 |
Medline Journal Info:
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Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 239-44 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Biomechanics Blood Transfusion Bone Marrow / physiology Child Epiphyses / physiopathology, radiography* Humans Humerus / physiopathology, radiography* Male Thalassemia / physiopathology*, therapy |
| Grant Support | |
ID/Acronym/Agency:
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RR125/RR/NCRR NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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