| Premalignant lesions of the larynx. A follow-up study. | |
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MedLine Citation:
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PMID: 2929313 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The object of this investigation was to evaluate in the long-term the risk of malignancy occurring in the larynx of patients with dysplasia in the laryngeal epithelium. Over an 8-year period, 1974-82, 170 patients underwent microlaryngoscopic examination of the larynx including biopsy, showing hyperplasia and/or keratosis with or without dysplasia in the laryngeal epithelium. Of these, 147 patients were examined, on an average, 5 years and 4 months later. All histological specimens were reviewed by the same pathologist. Of the patients initially showing mild dysplasia, 7.8% developed aggravation while 55.6% of the patients displaying moderate dysplasia had developed severe dysplasia or carcinoma. 93.2% were smokers. It is concluded that all patients with atypia in the laryngeal epithelium should be observed at regular intervals, but special attention should be given to patients showing moderate dysplasia or worse. |
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Authors:
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P E Højslet; V M Nielsen; D Palvio |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta oto-laryngologica Volume: 107 ISSN: 0001-6489 ISO Abbreviation: Acta Otolaryngol. Publication Date: 1989 Jan-Feb |
Date Detail:
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Created Date: 1989-05-10 Completed Date: 1989-05-10 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370354 Medline TA: Acta Otolaryngol Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 150-5 Citation Subset: IM |
Affiliation:
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ENT Department, Aalborg Hospital, Denmark. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Biopsy Female Humans Laryngeal Neoplasms / epidemiology, pathology* Male Middle Aged Precancerous Conditions / pathology* Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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