| Premalignant circumscribed palmar hypokeratosis: a new form of circumscribed palmar hypokeratosis? Case report and literature review. | |
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MedLine Citation:
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PMID: 19955702 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Circumscribed palmoplantar hypokeratosis (CPH) is a recently described dermatosis of unknown origin, of which 46 cases have been published so far. CPH affects predominantly adult women. It presents clinically with a sharply circumscribed annular erythematous depressed plaque rimmed by a slightly hyperkeratotic border, localized usually over the thenar or hypothenar eminences of the palm, less commonly on the soles. Histopathologically, it is characterized by an abrupt decrease in the horny layer thickness, forming a sharp stair between normal and involved skin. We report herein a new patient with CPH who presented an associated aspect of actinic keratosis, a hitherto unreported finding. This case suggests that CPH can undergo malignant transformation, probably as a result of actinic damage. On this occasion, a complete literature review of CPH is presented. |
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Authors:
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J Kanitakis; V Lora; B Balme; J Roby |
Publication Detail:
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Type: Case Reports; Journal Article; Review Date: 2009-12-02 |
Journal Detail:
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Title: Dermatology (Basel, Switzerland) Volume: 220 ISSN: 1421-9832 ISO Abbreviation: Dermatology (Basel) Publication Date: 2010 |
Date Detail:
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Created Date: 2010-03-05 Completed Date: 2010-06-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9203244 Medline TA: Dermatology Country: Switzerland |
Other Details:
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Languages: eng Pagination: 143-6 Citation Subset: IM |
Affiliation:
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Laboratory of Dermatopathology, Edouard Herriot Hospital, Lyon, France. jean.kanitakis@univ-lyon1.fr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Cell Transformation, Neoplastic / pathology* Diagnosis, Differential Female Humans Keratoderma, Palmoplantar / pathology* Keratosis, Actinic / pathology* Male Middle Aged Skin Neoplasms / pathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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