Document Detail

Preliminary results with iodine-125 seeds for permanent implantation in patients with localized prostatic cancer.
MedLine Citation:
PMID:  3423306     Owner:  NLM     Status:  MEDLINE    
Since August 1981, a permanent implantation with iodine-125 seeds has been performed in 41 patients with localized prostatic cancer. The seeds are implanted through a suprapubic incision. This gives the opportunity also to perform a diagnostic dissection of the regional lymph nodes. In five patients, the nodes were positive. In 4 out of these 5 patients bone metastases became manifest within one year. Two patients died of disseminated tumor, the first also had a local recurrence. Two other patients died shortly after treatment because of heart failure, while a third patient also died of heart failure, 2 years after implantation. Out of 31 patients with a follow-up period of 6 months or longer, distant metastases were found in four, in 2 followed by a local recurrence in the prostate. We can conclude that the preliminary results of this technique are encouraging with only three local recurrences in 41 patients. The prognostic value of positive lymph nodes was once again established.
J J Battermann; T A Boon; H J de Voogt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology     Volume:  10     ISSN:  0167-8140     ISO Abbreviation:  Radiother Oncol     Publication Date:  1987 Oct 
Date Detail:
Created Date:  1988-02-05     Completed Date:  1988-02-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8407192     Medline TA:  Radiother Oncol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  91-5     Citation Subset:  IM    
Department of Radiotherapy, University Hospital Utrecht, The Netherlands.
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MeSH Terms
Brachytherapy / methods*
Evaluation Studies as Topic
Iodine Radioisotopes / administration & dosage*
Lymphatic Metastasis
Neoplasm Recurrence, Local / epidemiology
Neoplasm Staging
Prostatic Neoplasms / pathology,  radiotherapy*
Reg. No./Substance:
0/Iodine Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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