| Preliminary results of radiotherapy for primary intraocular non-Hodgkin's lymphoma. | |
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MedLine Citation:
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PMID: 23343177 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Abstract This study aims to retrospectively evaluate the efficacy of radiotherapy for primary intraocular non-Hodgkin's lymphoma (PIOL). Between May 1998 and October 2010, 22 immunocompetent patients (4 men, 18 women; median age 70 years; range 53-79 years) were diagnosed with PIOL. Magnetic resonance imaging showed no intracranial involvement in any patient. Patients received radiotherapy median total dose of 30 Gy (range 30-40 Gy). Three-year overall survival, progression-free survival and local control rates were 89% (95% confidence interval [CI]: 75, 103), 49% (95% CI: 24, 73) and 95% (95% CI: 86, 105) over a median of 36 months of observation, respectively. Twelve patients (55%) had intracranial relapse at a median of 28 months after initiation of radiotherapy. Visual acuity improved or was stable in 81% of treated eyes. The only grade ≥ 3 toxicity was cataract formation (5 patients). Radiotherapy without chemotherapy for PIOL achieved high local control rates with acceptable toxicities. |
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Authors:
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Ryuji Mikami; Hidetsugu Nakayama; Hiroshi Goto; Keisuke Kimura; Sachika Nogi; Mitsuru Okubo; Naoto Kanesaka; Shinji Sugahara; Koichi Tokuuye |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-1-24 |
Journal Detail:
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Title: Leukemia & lymphoma Volume: - ISSN: 1029-2403 ISO Abbreviation: Leuk. Lymphoma Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-1-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9007422 Medline TA: Leuk Lymphoma Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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