Document Detail


Preliminary report: Correct diagnosis of sex in fetal cells isolated from cervical mucus during early pregnancy.
MedLine Citation:
PMID:  16401223     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study was to determine the accuracy of sexing fetal cells isolated from cervical mucus. Immunopositive cells identified using a fetal-specific antibody were isolated and subjected to genetic analysis. Fetal sex was predicted in all 22 samples, as confirmed by analysis of the corresponding placental tissue. This study validates the accuracy of our test for sex diagnosis and confirms the ability to effectively recover and analyse fetal cells from the cervical mucus during early pregnancy.
Authors:
Debbie Mantzaris; David Cram; Christine Healy; Donna Howlett; Gab Kovacs
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Australian & New Zealand journal of obstetrics & gynaecology     Volume:  45     ISSN:  0004-8666     ISO Abbreviation:  Aust N Z J Obstet Gynaecol     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2006-01-10     Completed Date:  2006-06-09     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0001027     Medline TA:  Aust N Z J Obstet Gynaecol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  529-32     Citation Subset:  IM    
Affiliation:
Monash IVF, Clayton, Victoria, Australia. dmantzaris@monashivf.edu.au
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MeSH Terms
Descriptor/Qualifier:
Adult
Cervix Mucus / cytology*
Female
Fetus / cytology*
Gestational Age
Humans
In Situ Hybridization, Fluorescence
Polymerase Chain Reaction / methods
Pregnancy
Risk Factors
Sampling Studies
Sensitivity and Specificity
Sex Determination (Analysis) / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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