Document Detail


Preliminary evidence for the presence of glutathione-s-transferase activity in mammalian and avian brain.
MedLine Citation:
PMID:  15622733     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Glutathione-S-transferase activity has been demonstrated in the brain of rabbit, guinea pig, rat, mouse, and pigeon. The activity was in the following order: rabbit > (guinea pig = mouse) > rat > pigeon. The activity of brain was about 1/3 to 1/9 of that present in liver depending upon the species. In the rat brain glutathione-S-transferase activity was found to be distributed equally in cerebrum, cerebellum, and brain stem and localized mainly in the organelle-free cytosol fraction.
Authors:
R Dixit; H Mukhtar; P K Seth; C R Murti
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Neurotoxicology     Volume:  2     ISSN:  0161-813X     ISO Abbreviation:  Neurotoxicology     Publication Date:  1981 Jan 
Date Detail:
Created Date:  2004-12-29     Completed Date:  2005-01-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7905589     Medline TA:  Neurotoxicology     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  193-6     Citation Subset:  IM    
Affiliation:
Industrial Toxicology Research Centre, Mahatma Gandhi Marg, Lucknow, India.
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MeSH Terms
Descriptor/Qualifier:
Animals
Brain / enzymology*
Columbidae
Cytosol / metabolism
Glutathione Transferase / metabolism*
Guinea Pigs
Mice
Rabbits
Rats
Subcellular Fractions / enzymology
Chemical
Reg. No./Substance:
EC 2.5.1.18/Glutathione Transferase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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