Document Detail


Preliminary evaluation of a new fibre-optic cerebral oximetry system.
MedLine Citation:
PMID:  18974439     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A new system for measuring the oxygen saturation of blood within tissue has been developed, for a variety of patient monitoring applications. A particular unmet need is in the central nervous system, and this project aims to devise a means for measuring blood oxygen saturation in the brain tissue of patients recovering from neurosurgery or head injury. Coupling light sources and a photodetector to optical fibres results in a probe small enough to pass through a cranial bolt of the type already in use for intra-cranial pressure monitoring. The development and evaluation of a two-wavelength fibre-optic reflectance photoplethysmography (PPG) system are described. It was found that good quality red and near-infrared PPG signals could be obtained from the finger using a fibre-optic probe. Experiments were conducted to find the inter-fibre spacings that yield signals most suitable for calculating oxygen saturation. Reliable signals could be obtained for inter-fibre spacings between 2 mm and 5 mm, the latter being the size of the maximum aperture in the cranial bolt. A preliminary measurement from human brain tissue is also presented.
Authors:
J P Phillips; R M Langford; P A Kyriacou; D P Jones
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Publication Detail:
Type:  Evaluation Studies; Journal Article     Date:  2008-10-30
Journal Detail:
Title:  Physiological measurement     Volume:  29     ISSN:  0967-3334     ISO Abbreviation:  Physiol Meas     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-11-28     Completed Date:  2009-02-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9306921     Medline TA:  Physiol Meas     Country:  England    
Other Details:
Languages:  eng     Pagination:  1383-96     Citation Subset:  IM    
Affiliation:
Anaesthetic Laboratory, St Bartholomew's Hospital, London EC1A 7BE, UK. j.p.phillips@qmul.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Amplifiers, Electronic
Brain Chemistry / physiology*
Humans
Infrared Rays
Light
Oximetry / instrumentation*,  methods
Photoplethysmography / instrumentation*,  methods
Safety
Signal Processing, Computer-Assisted
Software

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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