Document Detail


Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients.
MedLine Citation:
PMID:  3143549     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of the combined administration of gamma-aminobutyric acid (GABA) and phosphatidylserine was evaluated in a pilot study of 42 patients with drug-resistant epilepsy. The group included patients with complex partial seizures, simple partial seizures and absence seizures. Patients with complex partial seizures and simple partial seizures showed no significant improvement; on the other hand, there was a remarkable decrease in absence seizures, linearly related to the dose of GABA and phosphatidylserine. Side effects occurred in 9 patients and were usually mild.
Authors:
C Loeb; E Benassi; G P Bo; L Cocito; M Maffini; P Scotto
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Epilepsy research     Volume:  1     ISSN:  0920-1211     ISO Abbreviation:  Epilepsy Res.     Publication Date:  1987 May 
Date Detail:
Created Date:  1989-01-17     Completed Date:  1989-01-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8703089     Medline TA:  Epilepsy Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  209-12     Citation Subset:  IM    
Affiliation:
Clinica Neurologica dell'Università, Genoa, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Anticonvulsants / therapeutic use
Epilepsy / drug therapy*,  metabolism
Epilepsy, Absence / drug therapy*,  metabolism
Female
Humans
Male
Middle Aged
Phosphatidylserines / adverse effects,  therapeutic use*
gamma-Aminobutyric Acid / adverse effects,  therapeutic use*
Chemical
Reg. No./Substance:
0/Anticonvulsants; 0/Phosphatidylserines; 56-12-2/gamma-Aminobutyric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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