| Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients. | |
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MedLine Citation:
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PMID: 3143549 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effect of the combined administration of gamma-aminobutyric acid (GABA) and phosphatidylserine was evaluated in a pilot study of 42 patients with drug-resistant epilepsy. The group included patients with complex partial seizures, simple partial seizures and absence seizures. Patients with complex partial seizures and simple partial seizures showed no significant improvement; on the other hand, there was a remarkable decrease in absence seizures, linearly related to the dose of GABA and phosphatidylserine. Side effects occurred in 9 patients and were usually mild. |
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Authors:
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C Loeb; E Benassi; G P Bo; L Cocito; M Maffini; P Scotto |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Epilepsy research Volume: 1 ISSN: 0920-1211 ISO Abbreviation: Epilepsy Res. Publication Date: 1987 May |
Date Detail:
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Created Date: 1989-01-17 Completed Date: 1989-01-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8703089 Medline TA: Epilepsy Res Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 209-12 Citation Subset: IM |
Affiliation:
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Clinica Neurologica dell'Università, Genoa, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Anticonvulsants / therapeutic use Epilepsy / drug therapy*, metabolism Epilepsy, Absence / drug therapy*, metabolism Female Humans Male Middle Aged Phosphatidylserines / adverse effects, therapeutic use* gamma-Aminobutyric Acid / adverse effects, therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Anticonvulsants; 0/Phosphatidylserines; 56-12-2/gamma-Aminobutyric Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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