Document Detail


Preimplantation genetic screening: an effective testing for infertile and repeated miscarriage patients?
MedLine Citation:
PMID:  20671940     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Aneuploidy in pregnancy is known to increase with advanced maternal age (AMA) and associate with repeated implantation failure (RIF), and repeated miscarriage (RM). Preimplantation genetic screening (PGS) has been introduced into clinical practice, screening, and eliminating aneuploidy embryos, which can improve the chance of conceptions for infertility cases with poor prognosis. These patients are a good target group to assess the possible benefit of aneuploidy screening. Although practiced widely throughout the world, there still exist some doubts about the efficacy of this technique. Recent randomized trials were not as desirable as we expected, suggesting that PGS needs to be reconsidered. The aim of this review is to discuss the efficacy of PGS.
Authors:
Ning Wang; Ying-Ming Zheng; Lei Li; Fan Jin
Publication Detail:
Type:  Journal Article     Date:  2010-07-01
Journal Detail:
Title:  Obstetrics and gynecology international     Volume:  2010     ISSN:  1687-9597     ISO Abbreviation:  Obstet Gynecol Int     Publication Date:  2010  
Date Detail:
Created Date:  2010-07-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101517078     Medline TA:  Obstet Gynecol Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  120130     Citation Subset:  -    
Affiliation:
Department of Reproductive Endocrinology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China.
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