| Prehospital interventions to improve neurological outcome following cardiac arrest. | |
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MedLine Citation:
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PMID: 16969738 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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As many cases of cardiac arrest occur outside of the health care setting, prehospital treatment may dramatically affect patient outcomes. The three major interventions that have been studied are chest compressions and ventilation, electrical defibrillation, and medications. Recent studies show that increasing the rate of cardiopulmonary resuscitation (CPR), decreasing the rate of ventilation, and initiation of CPR prior to defibrillation may result in improved survival. Biphasic defibrillators can restore perfusing rhythms while minimizing myocardial injury. Public access to automatic defibrillators has been shown to increase the survival of cardiac arrest patients. Medications such as amiodarone, vasopressin, and thrombolytics also may have a role in the prehospital treatment of cardiac arrest. Recent advances in these areas will be reviewed with a discussion of the effect of each intervention on the restoration of circulation and neurological outcomes. |
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Authors:
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Charles M Little; Norman A Paradis; Kennon Heard |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Seminars in neurology Volume: 26 ISSN: 0271-8235 ISO Abbreviation: Semin Neurol Publication Date: 2006 Sep |
Date Detail:
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Created Date: 2006-09-13 Completed Date: 2006-11-01 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8111343 Medline TA: Semin Neurol Country: United States |
Other Details:
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Languages: eng Pagination: 380-6 Citation Subset: IM |
Affiliation:
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Division of Emergency Medicine, Department of Surgery, University of Colorado School of Medicine, Colorado Emergency Medicine Research Center, Denver, Colorado, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Arrhythmia Agents
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pharmacology,
therapeutic use Brain Infarction / etiology*, physiopathology, prevention & control* Cardiopulmonary Resuscitation / standards, trends Defibrillators / standards, trends Fibrinolytic Agents / pharmacology, therapeutic use Heart Arrest / complications*, physiopathology, therapy* Humans Hypoxia-Ischemia, Brain / etiology*, physiopathology, prevention & control* Treatment Outcome Vasoconstrictor Agents / pharmacology, therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Anti-Arrhythmia Agents; 0/Fibrinolytic Agents; 0/Vasoconstrictor Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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