Document Detail

Prehospital coronary thrombolysis. A new strategy in acute myocardial infarction.
MedLine Citation:
PMID:  3595223     Owner:  NLM     Status:  MEDLINE    
Thirty-four patients with acute myocardial infarction were treated prospectively using a new strategy of prehospital intravenous streptokinase given by a physician-operated mobile intensive care unit. The 29 prehospital-treated patients who had experienced no previous myocardial infarction were compared to a similar group treated with streptokinase inhospital. Patients receiving streptokinase in the prehospital phase of acute myocardial infarction had smaller infarcts and better residual myocardial function than the group given streptokinase inhospital in terms of peak creatinine phosphokinase, ejection fraction, computer-derived dysfunction index, and electrocardiographic QRS score. The only difference between these groups at baseline was the duration of pain prior to initiation of streptokinase therapy. There were no major complications related to prehospital administration of streptokinase.
A T Weiss; D G Fine; D Applebaum; S Welber; D Sapoznikov; C Lotan; M Mosseri; Y Hasin; M S Gotsman
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Chest     Volume:  92     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1987 Jul 
Date Detail:
Created Date:  1987-08-12     Completed Date:  1987-08-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  124-8     Citation Subset:  AIM; IM    
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MeSH Terms
Fibrinolytic Agents / administration & dosage*
Infusions, Intravenous
Middle Aged
Myocardial Infarction / classification,  drug therapy*,  physiopathology
Prospective Studies
Streptokinase / administration & dosage
Reg. No./Substance:
0/Fibrinolytic Agents; EC 3.4.-/Streptokinase

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