Document Detail

Prehospital 12-lead ST-segment monitoring improves the early diagnosis of acute coronary syndrome.
MedLine Citation:
PMID:  22115367     Owner:  NLM     Status:  MEDLINE    
AIMS/METHODS: We studied 620 patients who activated "911" for chest pain symptoms to determine the sensitivity and specificity of 12-lead electrocardiogram (ECG) ST-segment monitoring in the prehospital period (PH ECG) for diagnosing acute coronary syndrome (ACS) and to assess whether the addition of PH ECG signs of ischemia/injury to the initial hospital 12-lead ECG obtained in the emergency department would improve the diagnosis of ACS.
RESULTS: The sensitivity and specificity of the PH ECG were 65.4% and 66.4%. There was a significant increase in sensitivity (79.9%) and decrease in specificity (61.2%) when considered in conjunction with the initial hospital ECG (P < .001). Those with PH ECG ischemia/injury were more than 2.5 times likely to have an ACS diagnosis than those who had no PH ECG ischemia/injury (P < .001).
CONCLUSIONS: Prehospital ECG data obtained with 12-lead ST-segment monitoring provides diagnostic information about ACS above and beyond the initial hospital ECG.
Jessica K Zègre Hemsey; Kathleen Dracup; Kirsten Fleischmann; Claire E Sommargren; Barbara J Drew
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2011-11-23
Journal Detail:
Title:  Journal of electrocardiology     Volume:  45     ISSN:  1532-8430     ISO Abbreviation:  J Electrocardiol     Publication Date:    2012 May-Jun
Date Detail:
Created Date:  2012-04-23     Completed Date:  2012-08-31     Revised Date:  2013-12-10    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  266-71     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
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MeSH Terms
Acute Coronary Syndrome / diagnosis*,  epidemiology*
California / epidemiology
Early Diagnosis
Electrocardiography / methods*,  statistics & numerical data*
Emergency Medical Services / statistics & numerical data*
Reproducibility of Results
Sensitivity and Specificity
Grant Support
R01 NR007881/NR/NINR NIH HHS; R01 NR007881-03/NR/NINR NIH HHS; R01NR007881/NR/NINR NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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