Document Detail

Pregnancy toxemia and ketosis of ewes and does.
MedLine Citation:
PMID:  3264753     Owner:  NLM     Status:  MEDLINE    
Pregnancy toxemia of ewes and does appears to occur when the animal cannot meet the glucose demands of the fetal-placental unit and hypoglycemia develops. There is individual variation in susceptibility, and there may be basic differences in glucose metabolism between susceptible animals and nonsusceptible animals. Increased serum NEFA and ketone body concentrations accompany the disease, but clinical signs do not appear to develop in the absence of hypoglycemia. The diagnosis is based on history, clinical signs, and the finding of ketone bodies in the urine. Numerous metabolic abnormalities develop subsequent to hypoglycemia and hyperketonemia, and these affect the prognosis. Important secondary abnormalities include acidosis, dehydration, and renal failure. Therapy is frequently unsuccessful, but frequent administration of small doses of glucose appears to be beneficial, if the other abnormalities, such as acidosis and dehydration, are controlled. Prevention can be readily achieved by nutritional means and is far more rewarding than therapy. Ewes and does must be fed in relation to their changing energy needs throughout the reproductive cycle.
J V Marteniuk; T H Herdt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Veterinary clinics of North America. Food animal practice     Volume:  4     ISSN:  0749-0720     ISO Abbreviation:  Vet. Clin. North Am. Food Anim. Pract.     Publication Date:  1988 Jul 
Date Detail:
Created Date:  1989-02-16     Completed Date:  1989-02-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8511905     Medline TA:  Vet Clin North Am Food Anim Pract     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  307-15     Citation Subset:  IM    
Department of Large Animal Clinical Sciences, Michigan State University College of Veterinary Medicine, East Lansing.
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MeSH Terms
Acidosis / veterinary*
Goats / metabolism*
Ketosis / veterinary*
Lactation / metabolism
Pre-Eclampsia / veterinary*
Sheep Diseases / metabolism*

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