Document Detail

Pregnancy toxemia in a flock of sheep.
MedLine Citation:
PMID:  11128547     Owner:  NLM     Status:  MEDLINE    
A high prevalence of metabolic disease was evident in a large flock of sheep early in the lambing season. Pregnancy toxemia and secondary hypocalcemia were diagnosed on the basis of history, physical examination findings, and results of serum biochemical analyses. To decrease costs to the owner, pooled serum samples were used to determine the metabolic health status of the flock. Ewes close to the time of lambing were found to be in severe negative energy balance, which resulted in excessive fat mobilization as well as clinical signs associated with pregnancy toxemia and hepatic lipidosis. By nutrient analysis, it was determined that the ewes had an inadequate amount of fermentable carbohydrates, which provide glucose to support the additional nutrition required during late gestation. The diet provided to sheep during late gestation should contain sufficient glucose precursors to maintain adequate glucose availability to maternal and fetal tissues. To minimize the physiologic decline in dry-matter intake during late gestation (which results in accentuation of negative energy balance), high-quality feed ingredients should be fed to ewes during this period.
R J Van Saun
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American Veterinary Medical Association     Volume:  217     ISSN:  0003-1488     ISO Abbreviation:  J. Am. Vet. Med. Assoc.     Publication Date:  2000 Nov 
Date Detail:
Created Date:  2000-12-20     Completed Date:  2001-05-24     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  7503067     Medline TA:  J Am Vet Med Assoc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1536-9     Citation Subset:  IM    
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis 97331-4802, USA.
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MeSH Terms
Animal Feed / analysis*
Anorexia / veterinary
Blood Chemical Analysis
Carbohydrate Metabolism*
Fatty Acids / blood
Hypocalcemia / veterinary
Hypoglycemia / veterinary
Hypokalemia / veterinary
Ketone Bodies
Lipoproteins, VLDL / blood
Pre-Eclampsia / metabolism,  pathology,  veterinary*
Sheep Diseases / metabolism*
Reg. No./Substance:
0/Fatty Acids; 0/Ketone Bodies; 0/Lipoproteins, VLDL

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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