Document Detail

Pregnancy-specific protein B, progesterone concentrations and embryonic mortality during early pregnancy in dairy cows.
MedLine Citation:
PMID:  3397939     Owner:  NLM     Status:  MEDLINE    
Pregnancy-specific protein B (PSPB) and progesterone concentrations were determined by RIAs in venous plasma during early pregnancy after 177 artificial inseminations (AI) performed in 76 cows and 71 heifers. The females were bled at 24, 26, 30-35 days and approximately 70 days (for non-returns to oestrus) after AI. In non-pregnant females without extended CL maintenance (progesterone less than 1.5 ng/ml on Day 24) and or showing a normal time of return to oestrus (Group 1, N = 63), PSPB concentrations were undetectable whatever the stage after AI except in 2 cows. In pregnant animals (N = 83; Group 2) progesterone concentrations were greater than 10 ng/ml from Day 24 to the time of rectal palpation and PSPB concentrations rose continuously from 0.42 +/- 0.07 (s.e.m.) ng/ml (Day 24) to 4.06 +/- 0.3 ng/ml (time of rectal palpation). No coefficient of correlation between PSPB and progesterone concentrations was significant whatever the day of gestation studied. In cows with extended luteal function and subsequently found to be non-pregnant (late embryonic mortality) PSPB was undetectable (N = 21; Group 3) or detectable (N = 10; Group 4) at Days 24, 26 and/or 30-35 of pregnancy. At 24 and 26 days after AI progesterone concentrations were intermediate between those of Groups 1 and 2. At Day 24 females of Group 4 had higher progesterone concentrations than those of Group 3 (P less than 0.05), but no differences between these two groups existed at subsequent stages after AI.(ABSTRACT TRUNCATED AT 250 WORDS)
F Humblot; S Camous; J Martal; J Charlery; N Jeanguyot; M Thibier; R G Sasser
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of reproduction and fertility     Volume:  83     ISSN:  0022-4251     ISO Abbreviation:  J. Reprod. Fertil.     Publication Date:  1988 May 
Date Detail:
Created Date:  1988-08-26     Completed Date:  1988-08-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376367     Medline TA:  J Reprod Fertil     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  215-23     Citation Subset:  IM    
Laboratoire d'hormonologie, U.N.C.E.I.A., Maisons-Alfort, France.
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MeSH Terms
Fetal Death
Pregnancy, Animal / blood*
Progesterone / blood*
Reg. No./Substance:

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