Document Detail


Pregnancy-related pelvic girdle pain and its relationship with relaxin levels during pregnancy: a systematic review.
MedLine Citation:
PMID:  22310881     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: The present systematic review assessed the level of evidence for the association between relaxin levels and pregnancy-related pelvic girdle pain (PPGP) during pregnancy.
METHODS: PRISMA guidelines were followed to conduct this systematic review. Electronic search was carried out using six different databases. Observational cohorts, cross-sectional or case-control studies focused on the association between relaxin levels and PPGP during pregnancy were included. Studies selection was conducted by two reviewers who screened firstly for titles, then for abstracts and finally for full articles. Risk of bias was assessed using the Newcastle-Ottawa scale and the quality of evidence by the guidelines proposed by the Cochrane back review group.
RESULTS: 731 references were identified. Six articles met the inclusion criteria and were considered for this systematic review. The main reason for the studies exclusion was PPGP related to gynaecological reasons. Five studies were case-control and one study was a prospective cohort. Four studies were ranked as high while two were ranked as low quality. Among the high quality studies, three found no association between PPGP and relaxin levels.
CONCLUSIONS: Based on these findings, the level of evidence for the association between PPGP and relaxin levels was found to be low. PPGP assessment and controlling for risk factors were found to increase bias leaving uncertainty in interpretation of these findings and a need for further research.
Authors:
Daniela Aldabe; Daniel Cury Ribeiro; Stephan Milosavljevic; Melanie Dawn Bussey
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review     Date:  2012-02-04
Journal Detail:
Title:  European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society     Volume:  21     ISSN:  1432-0932     ISO Abbreviation:  Eur Spine J     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-09-27     Completed Date:  2013-04-19     Revised Date:  2013-09-03    
Medline Journal Info:
Nlm Unique ID:  9301980     Medline TA:  Eur Spine J     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1769-76     Citation Subset:  IM    
Affiliation:
School of Physical Education, University of Otago, 56 Union Street, Dunedin, 9016, New Zealand. daldabe@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Female
Humans
Pelvic Girdle Pain / blood*,  etiology
Pregnancy
Pregnancy Complications / blood*
Relaxin / blood*
Chemical
Reg. No./Substance:
9002-69-1/Relaxin
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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