| Pregnancy-related exacerbation of iatrogenic keratectasia despite corneal collagen crosslinking. | |
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MedLine Citation:
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PMID: 18571094 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Iatrogenic keratectasia after laser in situ keratomileusis (LASIK) represents a serious complication of refractive laser surgery. We describe a woman who developed bilateral iatrogenic keratectasia during her first pregnancy 26 months after LASIK. Corneal collagen crosslinking (CCL) with riboflavin and ultraviolet-A was performed in March 2005 (right eye) and April 2005 (left eye). This treatment stopped the progression and even caused the keratometric steepness to regress over a postoperative follow-up of 22 months, as demonstrated by preoperative and postoperative corneal topographies and maximum K-readings. During the patient's second pregnancy, the keratectasia exacerbated. To our knowledge, this is the first case showing exacerbation of keratectasia despite CCL and, as the exacerbation occurred only during pregnancy, suggesting that hormonal changes might affect corneal biomechanical stability. |
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Authors:
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Farhad Hafezi; Hans Peter Iseli |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of cataract and refractive surgery Volume: 34 ISSN: 0886-3350 ISO Abbreviation: J Cataract Refract Surg Publication Date: 2008 Jul |
Date Detail:
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Created Date: 2008-06-23 Completed Date: 2008-07-31 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8604171 Medline TA: J Cataract Refract Surg Country: United States |
Other Details:
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Languages: eng Pagination: 1219-21 Citation Subset: IM |
Affiliation:
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Institute for Refractive and Ophthalmic Surgery, Zurich, Switzerland. farhad.hafezi@iroc.ch |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Collagen / metabolism*, radiation effects Cornea / metabolism, pathology* Corneal Diseases / etiology* Corneal Topography Dilatation, Pathologic / etiology Female Humans Iatrogenic Disease* Keratomileusis, Laser In Situ Lasers, Excimer / therapeutic use Photosensitizing Agents / therapeutic use Pregnancy Pregnancy Complications* Riboflavin / therapeutic use Ultraviolet Rays |
| Chemical | |
Reg. No./Substance:
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0/Photosensitizing Agents; 83-88-5/Riboflavin; 9007-34-5/Collagen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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