Document Detail


Pregnancy rates and predictors in women with HIV/AIDS in Rio de Janeiro, Southeastern Brazil.
MedLine Citation:
PMID:  21412574     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To assess incidence and predictors of first pregnancy among women with HIV/AIDS.
METHODS: Prospective cohort study was conducted in Rio de Janeiro, southeastern Brazil, between 1996 and 2003. This study comprised 225 women with HIV/AIDS followed up until their first pregnancy or first censored event (hysterectomy, tubal ligation, menopause, 50 years of age, loss to follow-up, death or the end of December 2003). Pregnancy and abortion rates were estimated, and Cox proportional hazards models were used to identify baseline characteristics associated with pregnancy risk.
RESULTS: The women were followed up for 565 person/years with a median follow-up of 3 years per women. The mean age was 32 years (SD: 7), and 54.7% were white. There were 60 pregnancies in 39 women, and 18 were terminated (induced abortions), accounting for a rate of 6.9% and 2.1% women/year, respectively. Repeated pregnancies occurred in 33.3% of the women (13/39). Higher pregnancy risk was seen among younger women (HR=3.42; 95%CI: 1.69;6.95) and those living with their partners (HR=1.89; 95%CI: 1.00;3.57). Lower pregnancy risk was associated with higher education level (HR=0.43; 95%CI: 0.19;0.99) and use of antiretroviral therapy (HR=061; 95%CI: 0.31;1.17).
CONCLUSIONS: Lower pregnancy rates were found in our cohort than in the general population. Sociodemographic characteristics should be taken into consideration in the management of reproductive health in HIV-positive childbearing age women. Reproductive and family planning counseling must be incorporated into HIV/AIDS programs for women to help preventing HIV transmission to their partners and offspring.
Authors:
Ruth Khalili Friedman; Francisco I Bastos; Iuri Costa Leite; Valdiléa G Veloso; Ronaldo I Moreira; Sandra W Cardoso; Angela C Vasconcelos de Andrade; Michelle Cristina Sampaio; Judith Currier; Beatriz Grinsztejn
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Revista de saúde pública     Volume:  45     ISSN:  1518-8787     ISO Abbreviation:  Rev Saude Publica     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-03-17     Completed Date:  2011-08-18     Revised Date:  2014-09-08    
Medline Journal Info:
Nlm Unique ID:  0135043     Medline TA:  Rev Saude Publica     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  373-81     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Abortion, Induced / statistics & numerical data
Abortion, Spontaneous / epidemiology
Acquired Immunodeficiency Syndrome / drug therapy,  epidemiology*
Adult
Anti-Retroviral Agents / therapeutic use
Brazil / epidemiology
Female
HIV Infections / drug therapy,  epidemiology*
Humans
Incidence
Pregnancy
Pregnancy Rate*
Prospective Studies
Reproductive Behavior / statistics & numerical data
Risk Factors
Socioeconomic Factors
Grant Support
ID/Acronym/Agency:
K24 AI056933/AI/NIAID NIH HHS
Chemical
Reg. No./Substance:
0/Anti-Retroviral Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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