Document Detail


Pregnancy and pituitary disorders.
MedLine Citation:
PMID:  19934270     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Major hormonal changes emerge during pregnancy. The pituitary gland is one of the most affected organs with altered anatomy and physiology. The pituitary gland is enlarged as a result of lactotroph hyperplasia. Due to physiological changes in the pituitary and target hormone levels, binding globulins, and placental hormones, hormonal evaluation becomes more complex in pregnant women. As a consequence of physiological hormonal changes, the evaluation of pituitary functions in pregnant women is quite different from that done in the prepregnant state. Pituitary adenomas may cause problems by their hormone secretion that affects the mother and the fetus besides causing an increased risk of tumor growth. Furthermore, diagnosis, course, and treatment of pituitary diseases point out differences. The changes in anatomy and physiology of the pituitary gland during pregnancy are reviewed. Pituitary disorders namely Cushing's disease; acromegaly; prolactinoma; TSH-secreting, gonadotropin-producing, and clinically nonfunctioning adenomas; craniopharyngioma; and Sheehan's syndrome, which is one of the most common causes of hypopituitarism, lymphocytic hypophysitis, and hypopituitarism, in relation to pregnancy are discussed. Being aware of all this information will prevent any serious problems which mother and child will be exposed to.
Authors:
Z Karaca; F Tanriverdi; K Unluhizarci; F Kelestimur
Publication Detail:
Type:  Journal Article     Date:  2009-11-24
Journal Detail:
Title:  European journal of endocrinology / European Federation of Endocrine Societies     Volume:  162     ISSN:  1479-683X     ISO Abbreviation:  Eur. J. Endocrinol.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-22     Completed Date:  2010-03-15     Revised Date:  2010-05-25    
Medline Journal Info:
Nlm Unique ID:  9423848     Medline TA:  Eur J Endocrinol     Country:  England    
Other Details:
Languages:  eng     Pagination:  453-75     Citation Subset:  IM    
Affiliation:
Department of Endocrinology, Erciyes University Medical School, 38039 Kayseri, Turkey. fktimur@erciyes.edu.tr
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MeSH Terms
Descriptor/Qualifier:
Female
Humans
Pituitary Diseases / complications*,  physiopathology
Pituitary Gland / pathology,  physiopathology*
Pregnancy
Pregnancy Complications*
Comments/Corrections
Erratum In:
Eur J Endocrinol. 2010 Jun;162(6):1167

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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