Document Detail

Pregnancy outcomes in placental abruption.
MedLine Citation:
PMID:  17128829     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To determine the outcomes of pregnancies with placental abruption and to investigate the relationship between clinical maternal characteristics and poor perinatal outcomes. MATERIAL AND METHOD: A retrospective descriptive study was conducted to evaluate 103 cases of placental abruption delivered at King Chulalongkorn Memorial Hospital from 1995 to 2004. RESULTS: There were 111,375 singleton deliveries with 103 cases (0.92 in 1,000) complicated by placental abruption during the study period. Placental abruption attributed to maternal complications including hemorrhagic shock (19.4%), Couvelaire uterus (16.5%) and DIC (5.8%). The perinatal outcomes included low birth weight (65.0%), preterm (56.3%), severe birth asphyxia (16.5%) and perinatal death (16.5%). Placental abruption with pregnancy induced hypertension (PIH), DIC and blood transfusion had a significantly higher incidence of perinatal mortality than the remainder (odds ratio [OR] 4.16, 95% confidence interval [CI] 1.41-12.24; OR 12.92, 95%CI 2.15-77.80 and OR 3.93, 95%CI 1.27-12.19, respectively). Placental abruption with Couvelaire uterus had a significantly higher incidence of severe birth asphyxia than the remainder (OR 3.72, 95%CI 1.14-2.09). CONCLUSION: Placental abruption had a profound impact on both maternal and perinatal complications including DIC, Couvelaire uterus, severe birth asphyxia and perinatal death. The relationship between PIH, DIC, blood transfusion and Couvelaire uterus with poor perinatal outcomes were found Therefore, placental abruption with these clinical characteristics should be closely monitored and prompt delivery should be carried out at tertiary care centers with adequate maternal-neonatal intensive care facilities.
Amornrath Pitaphrom; Nares Sukcharoen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  89     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-11-28     Completed Date:  2007-10-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  Thailand    
Other Details:
Languages:  eng     Pagination:  1572-8     Citation Subset:  IM    
Department of Obstetrics & Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand.
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MeSH Terms
Abruptio Placentae / epidemiology*,  etiology
Asphyxia Neonatorum / epidemiology,  etiology
Disseminated Intravascular Coagulation / complications
Fetal Death
Infant, Low Birth Weight
Infant, Newborn
Pregnancy Outcome*
Retrospective Studies
Risk Factors
Shock, Hemorrhagic / complications

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