Document Detail

Pregnancy outcomes in patients with sickle cell disease in Enugu, Nigeria.
MedLine Citation:
PMID:  17937165     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Pregnancy in patients with sickle cell disease (SCD) is associated with increased maternal and foetal morbidity and mortality. The objective of this study was to review the pregnancy outcomes in patients with SCD as seen at the University of Nigeria Teaching Hospital(UNTH), Enugu, South-eastern Nigeria. METHODS: This is a retrospective study. The data extracted from the patients' case files include the age, parity, gestational age at booking and complications of disease and pregnancy during the antenatal period, labour and puerperium. Fetal outcomes were also reviewed. RESULTS: During the 30-year period under study (1975-2004), only 10 pregnant women with sickle cell disease were documented to have been attended to. Pregnancies were characterized by high maternal and fetal morbidity and mortality. Maternal complications identified were maternal mortality, lobar pneumonia, HIV and recurrent malaria infections, candidiasis, bone pain crises, haemolytic crises, pseudotoxaemia and pre-eclampsia. Fetal complications included intra-uterine fetal deaths, still births, low birth weights, and breech presentation. CONCLUSION: From this study, it seems that female SCD patients present more rarely with pregnancy in South-eastern compared to South-western Nigeria. However, the spectrum of complications seen is similar to that recorded in other studies.
S Ocheni; H E Onah; O G Ibegbulam; M I Eze
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria     Volume:  16     ISSN:  1115-2613     ISO Abbreviation:  Niger J Med     Publication Date:    2007 Jul-Sep
Date Detail:
Created Date:  2007-10-16     Completed Date:  2007-11-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888321     Medline TA:  Niger J Med     Country:  Nigeria    
Other Details:
Languages:  eng     Pagination:  252-5     Citation Subset:  IM    
Department of Haematology & Immunology, University of Nigeria Teaching Hospital, Enugu, Nigeria.
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MeSH Terms
Anemia, Sickle Cell / complications*,  epidemiology
Nigeria / epidemiology
Pregnancy Complications / epidemiology,  etiology*
Pregnancy Outcome*
Retrospective Studies
Risk Factors

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