| Pregnancy outcomes in oocyte donation recipients: vaginal gel versus intramuscular injection progesterone replacement. | |
| | |
MedLine Citation:
|
PMID: 22310935 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
PURPOSE: Compare outcomes with vaginal gel versus intramuscular progesterone replacement in donor oocyte recipients. METHODS: A single-center retrospective analysis (January 2004-December 2006) evaluated pregnancy outcomes (serum human chorionic gonadotropin, implantation, clinical pregnancy, delivery, total pregnancy loss rates) for 225 recipients of embryos from donor (aged <32 years) oocytes. Vaginal progesterone gel (Crinone® 8%; 90 mg twice daily; n = 105) or intramuscular progesterone (50 mg once daily; n = 120) was started the afternoon of oocyte retrieval and continued until a negative pregnancy test or 10 weeks' gestation. RESULTS: There were no statistically significant differences between groups for the five pregnancy outcomes; numerical results favored vaginal progesterone in all cases. Confidence intervals showed vaginal gel was within, or <1% from, a noninferiority limit of 10% versus intramuscular progesterone for four of five pregnancy outcomes. CONCLUSIONS: Pregnancy outcomes were comparable for progesterone replacement with vaginal gel and intramuscular progesterone in an oocyte donation program. |
| | |
Authors:
|
Brian M Berger; James A Phillips |
Related Documents
:
|
16949405 - The effect of maternal oxygen administration on fetal pulse oximetry during labor in fe... 1870055 - The advantages of computerized fetal heart rate analysis. 443305 - Fetal heart rate acceleration in labor: excellent prognostic indicator. 12423865 - The effect of a nitric oxide donor on fetal heart rate patterns in patients with hypert... 19037175 - Pregnancy exposure to serotonin reuptake inhibitors and the risk of spontaneous abortions. 761655 - Postnatal formation of alveoli: interstitial events and physiologic consequences. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-2-4 |
Journal Detail:
|
Title: Journal of assisted reproduction and genetics Volume: - ISSN: 1573-7330 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
|
Created Date: 2012-2-7 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9206495 Medline TA: J Assist Reprod Genet Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Boston IVF, Inc., 130 Second Avenue, Waltham, MA, 02451, USA, BBerger@BOSTONIVF.com. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Hippocampal Drebrin Loss in Mild Cognitive Impairment.
Next Document: Construction of adjacent spiro-quaternary and tertiary stereocenters through phosphine-catalyzed asy...