Document Detail

Pregnancy outcomes among women with panic disorder - do panic attacks during pregnancy matter?
MedLine Citation:
PMID:  19428119     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To assess the risks that maternal panic disorder (PD) during pregnancy contribute to adverse pregnancy outcomes, with the effects further specifically differentiated into mothers who experienced a panic attack during pregnancy and those who did not. METHOD: This study linked two nationwide population-based datasets: the birth certificate registry and the Taiwan National Health Insurance Research Dataset. We identified a total of 371 women who gave birth from 2001 to 2003, who had been diagnosed with PD within 2 years prior to the index delivery, together with 1585 matched women without this chronic disease as a comparison cohort. Multivariate logistic regression analyses were performed to estimate odds ratios. RESULTS: Results indicated that compared to women without chronic disease, PD mothers who experienced panic manifestations during pregnancy and those who did not were independently associated with respective 2.29- (95% confidence interval (CI)=1.14-4.60) and 1.45-fold (95% CI=1.03-2.04) increased risks of having small-for-gestational-age infants. Further, for PD mothers who experienced a panic attack during gestation, the adjusted odds ratio for having a preterm delivery was 2.54 (95% CI=1.09-5.93), whereas no significant difference was identified between PD women who did not have a panic attack during pregnancy and women without PD. LIMITATION: Our study was unable to investigate the effects of such risk factors as dietary habits, cigarette smoking, and alcohol use in the regression model. CONCLUSION: We conclude that prenatal PD, particularly the occurrence of panic attacks during pregnancy, was associated with adverse birth outcomes.
Yi-Hua Chen; Herng-Ching Lin; Hsin-Chien Lee
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of affective disorders     Volume:  120     ISSN:  1573-2517     ISO Abbreviation:  J Affect Disord     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-12-16     Completed Date:  2010-03-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7906073     Medline TA:  J Affect Disord     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  258-62     Citation Subset:  IM    
School of Public Health, Taipei Medical University, Taipei, Taiwan.
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MeSH Terms
International Classification of Diseases
Panic Disorder / diagnosis,  epidemiology*,  psychology*
Pregnancy Complications / epidemiology
Pregnancy Outcome*
Severity of Illness Index
Young Adult

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