Document Detail

Pregnancy outcomes after laparoscopic ovarian drilling in women with polycystic ovarian syndrome.
MedLine Citation:
PMID:  16598331     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To study whether there is an increased risk of glucose intolerance and hypertensive complications during pregnancy in women with polycystic ovarian syndrome (PCOS) who conceived after laparoscopic ovarian drilling and to investigate if there is an adverse pregnancy outcome. METHODS: This prospective study took place at Salmaniya Medical Complex in Bahrain, between June 1996 and June 2003. We compared the pregnancy and neonatal outcomes of 134 patients with PCOS who were treated with laparoscopic ovarian drilling with 479 pregnant women without PCOS (controls). We used the multiple logistic regression analysis to assess the risk of PCOS on impaired glucose tolerance (IGT), gestational diabetes mellitus (GDM), hypertensive disorders in pregnancy (HDP) and premature delivery. RESULTS: Subjects with PCOS had a significantly greater prepregnancy body mass index, prevalence of obesity and nulliparity as compared with controls. The incidence of IGT (p=0.007), GDM (p=0.01) and HDP (p=0.001) were significantly higher in pregnant PCOS compared with the control group. There were no significant differences in the neonatal outcomes and prevalence of premature delivery between the 2 study groups. When non-obese PCOS patients were compared with non-obese controls, the incidence of GDM (p=0.04) and HDP (p=0.004) were still significantly higher in the former. The prevalence of pregnancy complications were not significantly different when obese PCOS were compared with obese control patients. The PCOS was demonstrated as a risk factor for IGT (p=0.05), GDM (p=0.03) and HDP (p=0.03), but not for premature delivery. CONCLUSION: Women with PCOS who conceived after the drilling were at higher risk of IGT, GDM and HDP, and this risk seemed to be independent of maternal obesity.
Eftekhar H Al-Ojaimi
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Saudi medical journal     Volume:  27     ISSN:  0379-5284     ISO Abbreviation:  Saudi Med J     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-04-06     Completed Date:  2006-08-01     Revised Date:  2008-06-23    
Medline Journal Info:
Nlm Unique ID:  7909441     Medline TA:  Saudi Med J     Country:  Saudi Arabia    
Other Details:
Languages:  eng     Pagination:  519-25     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Salmaniya Meidcal Complex, Ministry of Health, Kingdom of Bahrain.
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MeSH Terms
Body Mass Index
Case-Control Studies
Diabetes, Gestational / epidemiology*
Follow-Up Studies
Glucose Intolerance / epidemiology*
Hypertension, Pregnancy-Induced / epidemiology*
Polycystic Ovary Syndrome / surgery*
Pregnancy Outcome*
Prospective Studies

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