Document Detail


Pregnancy outcome in women with prosthetic heart valves.
MedLine Citation:
PMID:  12521884     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
The pregnancy outcome of 59 pregnancies in 38 women with prosthetic heart valves, managed at a tertiary referral centre from 1989-98 were reviewed. Ten women underwent valve replacement during pregnancy. The main outcome measures were major maternal complications and perinatal outcome. The maternal mortality rate for pregnancies following valve replacement surgery was 6.1%, with a 21% pregnancy loss before viability and a perinatal loss of 8%. Major morbidity in this group was as follows: haemorrhage 29.8%, cardiac failure 12.8%, thromboembolism 8.5%, infective endocarditis 6.4% and valve thrombosis 4.3%. No maternal mortality occurred among those who underwent valve replacement during pregnancy but their perinatal loss was 25%. We conclude that although maternal mortality and morbidity rates in women with prosthetic heart valves who became pregnant were high, the perinatal outcome was good except for women who underwent valve replacement during pregnancy who experienced a high perinatal loss rate.
Authors:
D R Hall; J Olivier; G J Rossouw; D Grové; A F Doubell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology     Volume:  21     ISSN:  0144-3615     ISO Abbreviation:  J Obstet Gynaecol     Publication Date:  2001 Mar 
Date Detail:
Created Date:  2005-09-13     Completed Date:  2005-10-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309140     Medline TA:  J Obstet Gynaecol     Country:  England    
Other Details:
Languages:  eng     Pagination:  149-53     Citation Subset:  -    
Affiliation:
Department of Obstetrics and Gynaecology, Tygerberg Hospital and University of Stellenbosch, MRC Perinatal Mortality Research Unit, South Africa. drh@gerga.sunac.za
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