Document Detail


Pregnancy outcome in women with primary renal disease.
MedLine Citation:
PMID:  10804948     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: The preconception and intraconception parameters that are relevant to outcome in women with underlying renal disease remain controversial. OBJECTIVES: To analyze the types and frequencies of short- and long-term (2 years after delivery) maternal and neonatal complications in 38 patients with primary renal disease (46 pregnancies), most of them with mild renal insufficiency. METHODS: Logistic regression models were formulated to predict successful outcome. RESULTS: Successful pregnancy outcome (live, healthy infant without severe handicap 2 years after delivery) was observed in 98% of the patients with primary renal disease. Factors found to be significantly predictive of successful outcome were absence of pre-existing hypertension, in addition to low preconception serum uric acid level. CONCLUSIONS: Most women with primary renal disease who receive proper prenatal care have a successful pregnancy outcome. Worse pregnancy outcome was observed in women with moderate or severe renal failure. Fitted logistic models may provide useful guidelines for counseling women with preexisting renal disease about their prospects for a successful pregnancy in terms of immediate and long-term maternal and neonatal outcome.
Authors:
J Bar; R Orvieto; Y Shalev; Y Peled; Y Pardo; U Gafter; Z Ben-Rafael; R Chen; M Hod
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Israel Medical Association journal : IMAJ     Volume:  2     ISSN:  1565-1088     ISO Abbreviation:  Isr. Med. Assoc. J.     Publication Date:  2000 Feb 
Date Detail:
Created Date:  2000-05-24     Completed Date:  2000-05-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100930740     Medline TA:  Isr Med Assoc J     Country:  ISRAEL    
Other Details:
Languages:  eng     Pagination:  178-81     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Rabin Medical Center (Beilinson Campus), Petah Tiqva, Israel. bar1@netvision.net.il
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MeSH Terms
Descriptor/Qualifier:
Female
Follow-Up Studies
Humans
Infant, Newborn
Kidney Diseases / complications*,  diagnosis
Kidney Failure, Chronic / complications,  diagnosis
Logistic Models
Pregnancy
Pregnancy Complications*
Pregnancy Outcome*
Prognosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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