| Pregnancy outcome in recurrent aborters is not influenced by Chlamydia IgA and/or G. | |
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MedLine Citation:
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PMID: 15667525 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PROBLEM: It is unclear whether chlamydia infection influences the miscarriage rate and immunological factors in patients with recurrent miscarriage. METHOD OF STUDY: Chlamydia DNA, IgA and IgG to Chlamydia trachomatis, natural killer cell activity, complement 3 (C3), C4, hemolytic complement, antinuclear antibodies, antiphospholipid antibodies, prolactin, activated partial thromboplastin time, prothrombin time and fibrinogen were examined in 504 patients with a history of two or more consecutive first-trimester miscarriages. Subsequent pregnancy outcomes were compared between cases with and without antibodies to C. trachomatis. RESULTS: Totals of 10 of 30 and 48 of 201 patients receiving no medication miscarried subsequently with and without chlamydia infection. Chlamydia IgA and/or IgG were associated with a high level of C3 but not other immunological and coagulatory parameters. CONCLUSION: Antibodies to C. trachomatis do not influence subsequent pregnancy outcome in patients with a history of recurrent miscarriage. |
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Authors:
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Mayumi Sugiura-Ogasawara; Yasuhiko Ozaki; Tamao Nakanishi; Yoshiaki Kumamoto; Kaoru Suzumori |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of reproductive immunology (New York, N.Y. : 1989) Volume: 53 ISSN: 1046-7408 ISO Abbreviation: Am. J. Reprod. Immunol. Publication Date: 2005 Jan |
Date Detail:
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Created Date: 2005-01-25 Completed Date: 2005-05-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8912860 Medline TA: Am J Reprod Immunol Country: Denmark |
Other Details:
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Languages: eng Pagination: 50-3 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Nagoya City University Medical School, Nagoya, Japan. og.mym@med.nagoya-cu.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Habitual
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immunology* Adult Chlamydia Infections / immunology* Chlamydia trachomatis / immunology Female Humans Immunoglobulin A / immunology* Immunoglobulin G / immunology* Pregnancy Pregnancy Outcome* |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulin A; 0/Immunoglobulin G |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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