| Pregnancy outcome in primigravidae with late onset hypertensive disease. | |
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MedLine Citation:
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PMID: 10685316 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The perinatal mortality associated with pre-eclampsia is extremely high and it is mainly associated with early onset disease in multiparous women. Hypertension without proteinuria in late pregnancy may not be associated with high perinatal mortality rates. OBJECTIVE: To establish the perinatal outcome in primigravidae women with hypertension occurring in late pregnancy, that is, at thirty fourth week or later. DESIGN: Prospective case-control study. SETTING: Labour ward of King Edward VIII Hospital, Durban, South Africa. PATIENTS: Three hundred and twenty two primigravidae consisting of 161 hypertensives and 161 controls. MAIN OUTCOME MEASURES: Maternal and foetal morbidity and mortality. RESULTS: The hypertensive group was divided into those with proteinuria (group a) and without proteinuria (group b). The mean birthweight of babies born to proteinuric hypertensives was significantly lower than that of hypertensives without proteinuria and the normotensive group (2.4 kg (a) versus 2.8 kg (b) versus 3.02 kg (c) respectively--a versus b, p = 0.0001; a versus c, p = 0.001; b versus c, p = 0.009). There were nine perinatal deaths and all occurred in the proteinuric hypertension group. CONCLUSION: Primigravidae with late onset proteinuric hypertension had smaller babies and higher perinatal mortality than their aproteinuric hypertensive and normotensive controls. |
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Authors:
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J Moodley; M Mphatsoe; E Gouws |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: East African medical journal Volume: 76 ISSN: 0012-835X ISO Abbreviation: East Afr Med J Publication Date: 1999 Sep |
Date Detail:
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Created Date: 2000-03-09 Completed Date: 2000-03-09 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372766 Medline TA: East Afr Med J Country: KENYA |
Other Details:
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Languages: eng Pagination: 490-4 Citation Subset: IM |
Affiliation:
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Pregnancy Hypertension Research Unit, Faculty of Medicine, University of Natal, South Africa. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Case-Control Studies Female Humans Hypertension / mortality* Infant Mortality Infant, Newborn Maternal Mortality Parity* Pre-Eclampsia / mortality* Pregnancy Pregnancy Complications, Cardiovascular / mortality* Pregnancy Outcome / epidemiology* Pregnancy Trimester, Third Prenatal Care / standards Prospective Studies South Africa / epidemiology |
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