Document Detail

Pregnancy outcome in primigravidae with late onset hypertensive disease.
MedLine Citation:
PMID:  10685316     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The perinatal mortality associated with pre-eclampsia is extremely high and it is mainly associated with early onset disease in multiparous women. Hypertension without proteinuria in late pregnancy may not be associated with high perinatal mortality rates. OBJECTIVE: To establish the perinatal outcome in primigravidae women with hypertension occurring in late pregnancy, that is, at thirty fourth week or later. DESIGN: Prospective case-control study. SETTING: Labour ward of King Edward VIII Hospital, Durban, South Africa. PATIENTS: Three hundred and twenty two primigravidae consisting of 161 hypertensives and 161 controls. MAIN OUTCOME MEASURES: Maternal and foetal morbidity and mortality. RESULTS: The hypertensive group was divided into those with proteinuria (group a) and without proteinuria (group b). The mean birthweight of babies born to proteinuric hypertensives was significantly lower than that of hypertensives without proteinuria and the normotensive group (2.4 kg (a) versus 2.8 kg (b) versus 3.02 kg (c) respectively--a versus b, p = 0.0001; a versus c, p = 0.001; b versus c, p = 0.009). There were nine perinatal deaths and all occurred in the proteinuric hypertension group. CONCLUSION: Primigravidae with late onset proteinuric hypertension had smaller babies and higher perinatal mortality than their aproteinuric hypertensive and normotensive controls.
J Moodley; M Mphatsoe; E Gouws
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  East African medical journal     Volume:  76     ISSN:  0012-835X     ISO Abbreviation:  East Afr Med J     Publication Date:  1999 Sep 
Date Detail:
Created Date:  2000-03-09     Completed Date:  2000-03-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372766     Medline TA:  East Afr Med J     Country:  KENYA    
Other Details:
Languages:  eng     Pagination:  490-4     Citation Subset:  IM    
Pregnancy Hypertension Research Unit, Faculty of Medicine, University of Natal, South Africa.
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MeSH Terms
Case-Control Studies
Hypertension / mortality*
Infant Mortality
Infant, Newborn
Maternal Mortality
Pre-Eclampsia / mortality*
Pregnancy Complications, Cardiovascular / mortality*
Pregnancy Outcome / epidemiology*
Pregnancy Trimester, Third
Prenatal Care / standards
Prospective Studies
South Africa / epidemiology

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