Document Detail


Pregnancy outcome in patients with primary Sjögren's syndrome. a case-control study.
MedLine Citation:
PMID:  16142869     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To study the outcome of pregnancy in patients with primary Sjögren's syndrome (pSS). METHODS: A questionnaire covering demographic data and the outcome of pregnancies was answered by 58 patients with pSS and 157 controls. For 36 patients and 93 controls, we analyzed detailed data about pregnancy, birth, and status of the newborn from the Medical Birth Registry of Norway (MFR) for birth order one, 2, and 3. Thirty-two of 36 patients registered in MFR were diagnosed with pSS after the last birth. RESULTS: Pregnancy outcomes were not different in patients compared to controls. Two patients (3.4%) reported giving birth to a child with congenital heart block. CONCLUSION: PSS had no impact on pregnancy outcome before disease onset. The most important condition associated with pSS in anti-SSA positive mothers was congenital heart block in the offspring.
Authors:
Hans-Jacob Haga; Clara Gram Gjesdal; Hege Svean Koksvik; Johan Fredrik Skomsvoll; Lorentz M Irgens; Monika Ostensen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of rheumatology     Volume:  32     ISSN:  0315-162X     ISO Abbreviation:  J. Rheumatol.     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-09-05     Completed Date:  2005-11-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7501984     Medline TA:  J Rheumatol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  1734-6     Citation Subset:  IM    
Affiliation:
Department of Rheumatology, Esbjerg Central Hospital, 6700 Esbjerg, Denmark. HJH@ribeamt.dk
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Case-Control Studies
Cohort Studies
Female
Gestational Age
Humans
Incidence
Infant, Newborn
Maternal Age
Middle Aged
Norway / epidemiology
Pregnancy
Pregnancy Complications / diagnosis,  epidemiology*
Pregnancy Outcome*
Pregnancy, High-Risk*
Probability
Questionnaires
Reference Values
Risk Assessment
Sjogren's Syndrome / complications,  diagnosis*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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