Document Detail

Pregnancy outcome after laparoscopic cryomyolysis of uterine myomas: report of nine cases.
MedLine Citation:
PMID:  16527717     Owner:  NLM     Status:  MEDLINE    
STUDY OBJECTIVE: To assess pregnancy course and outcome after laparoscopic cryomyolysis. DESIGN: Open, one-arm, observational clinical pilot study. (Canadian Task Force classification II). SETTING: University-affiliated public hospital. PATIENTS: Nine women who underwent laparoscopic cryomyolysis, with nine pregnancies observed. INTERVENTION: Laparoscopic cryomyolysis was performed by penetrating along the long axis of the myoma and provoking freezing at temperature -197 degrees C. MEASUREMENTS AND MAIN RESULTS: After laparoscopic-directed cryomyolysis, pregnant women were evaluated by physical and ultrasonographics examinations. The median time elapsed between cryomyolysis and pregnancy was 14 months (range 7-39 months). At the beginning of pregnancy, the mean volume of myomas was 30.4 mL (range 1.8-124.6 mL). During the first 20 gestational weeks, the mean increase in volume of the nine cryo-treated myomas was 71.1% (range 21.8%-97.7%); the volume of two myomas remained stationary, and two new myomas appeared. Two patients had early miscarriage. Seven pregnancies had a regular course. Four women delivered vaginally, and three by cesarean section. There were no complications in pregnancy, postpartum, and puerperium. No cases of uterine rupture were observed. CONCLUSIONS: The results of this series of nine pregnancies after laparoscopic cryomyolysis are promising. Laparoscopic cryomyolysis does not compromise a good pregnancy outcome and vaginal delivery. These preliminary data need to be confirmed by larger studies.
Andrea Ciavattini; Dimitrios Tsiroglou; Pietro Litta; Maddalena Vichi; Andrea Luigi Tranquilli
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of minimally invasive gynecology     Volume:  13     ISSN:  1553-4650     ISO Abbreviation:  -     Publication Date:    2006 Mar-Apr
Date Detail:
Created Date:  2006-03-10     Completed Date:  2006-07-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  101235322     Medline TA:  J Minim Invasive Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  141-4     Citation Subset:  IM    
Institute of Obstetrics and Gynecology, Università Politecnica delle Marche, Ancona, USA.
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MeSH Terms
Apgar Score
Cryosurgery / methods*
Follow-Up Studies
Gestational Age
Hospitals, University
Infant, Newborn
Laparoscopy / methods*
Leiomyoma / diagnosis,  surgery*
Maternal Age
Pilot Projects
Pregnancy Complications, Neoplastic / diagnosis,  surgery*
Pregnancy Outcome*
Prospective Studies
Risk Assessment
Treatment Outcome
Uterine Neoplasms / diagnosis,  surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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