Document Detail


Pregnancy-onset habitual snoring, gestational hypertension, and preeclampsia: prospective cohort study.
MedLine Citation:
PMID:  22999158     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: This study aimed to prospectively examine the impact of chronic vs pregnancy-onset habitual snoring on gestational hypertension, preeclampsia, and gestational diabetes.
STUDY DESIGN: Third-trimester pregnant women were recruited from a large, tertiary medical center from March 2007 through December 2010 and screened for the presence and duration of habitual snoring, as a known marker for sleep-disordered breathing. Clinical diagnoses of gestational hypertension, preeclampsia, and gestational diabetes were obtained.
RESULTS: Of 1719 pregnant women, 34% reported snoring, with 25% reporting pregnancy-onset snoring. After adjusting for confounders, pregnancy-onset, but not chronic, snoring was independently associated with gestational hypertension (odds ratio, 2.36; 95% confidence interval, 1.48-3.77; P < .001) and preeclampsia (odds ratio, 1.59; 95% confidence interval, 1.06-2.37; P = .024) but not gestational diabetes.
CONCLUSION: New-onset snoring during pregnancy is a strong risk factor for gestational hypertension and preeclampsia. In view of the significant morbidity and health care costs associated with hypertensive diseases of pregnancy, simple screening of pregnant women may have clinical utility.
Authors:
Louise M O'Brien; Alexandra S Bullough; Jocelynn T Owusu; Kimberley A Tremblay; Cynthia A Brincat; Mark C Chames; John D Kalbfleisch; Ronald D Chervin
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Publication Detail:
Type:  Journal Article     Date:  2012-09-07
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  207     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-23     Completed Date:  2013-02-05     Revised Date:  2013-12-04    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  487.e1-9     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2012 Mosby, Inc. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Adult
Case-Control Studies
Cohort Studies
Diabetes, Gestational / etiology*
Female
Humans
Hypertension, Pregnancy-Induced / etiology*
Incidence
Logistic Models
Odds Ratio
Pre-Eclampsia / etiology*
Pregnancy
Pregnancy Complications*
Pregnancy Trimester, Third
Prevalence
Prospective Studies
Snoring / etiology*
Young Adult
Grant Support
ID/Acronym/Agency:
K23 HL095739/HL/NHLBI NIH HHS; R21 HL087819/HL/NHLBI NIH HHS; R21 HL089918/HL/NHLBI NIH HHS; UL1 RR024986/RR/NCRR NIH HHS
Comments/Corrections
Comment In:
Am J Obstet Gynecol. 2013 Jun;208(6):507-8   [PMID:  23333550 ]
Am J Obstet Gynecol. 2013 Jun;208(6):507   [PMID:  23333545 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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