Document Detail


Pregnancy and the nephrotic syndrome.
MedLine Citation:
PMID:  5762644     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nineteen patients with nephrotic syndrome, 13 with histological diagnosis, were studied throughout 31 pregnancies. Eight were diagnosed for the first time during pregnancy.Antenatal problems due to severe oedema, urinary tract infection, and refractory orthochromic anaemia were encountered. Eight patients were hypertensive at booking, and in two of these pregnancy was terminated; three others had a significant increase in blood pressure. In 12 of the remaining pregnancies a rise in blood pressure of 20 mm. Hg or more occurred towards term.There were 29 live births (including one set of twins), one stillbirth due to a cord accident, and one neonatal death. The infant birth weight, apart from being affected by hypertension, was related to the maternal serum albumin level.The patients have been under observation for up to 20 years. Fifteen have not shown any deterioration of renal function during the prolonged period of observation. One developed oliguric renal failure immediately post partum and three others died, two, four, and 12 years after their pregnancies.
Authors:
J W Studd; J D Blainey
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British medical journal     Volume:  1     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1969 Feb 
Date Detail:
Created Date:  1969-02-28     Completed Date:  1969-02-28     Revised Date:  2010-10-26    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  276-80     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Anemia / complications
Birth Weight
Edema / complications
Female
Follow-Up Studies
Humans
Hypertension
Nephrotic Syndrome / complications*,  pathology
Pregnancy
Pregnancy Complications*
Pregnancy Complications, Cardiovascular
Urinary Tract Infections / complications
Comments/Corrections

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