Document Detail


Pregnancy and the liver.
MedLine Citation:
PMID:  22082978     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In pregnancy the liver can be affected by diseases specific to pregnancy as well as unrelated conditions. The possible effect of the disease and its management on both the fetus and mother must be considered. Several physiological changes occur during pregnancy as liver metabolism is altered. Serum protein concentrations fall, with a decrease in serum albumin in part the result of the dilutional effect of an increase in plasma volume. Alanine transaminase and aspartate transaminase levels decrease (Table 1), complicating the diagnosis of disorders involving subtle changes in liver function. Alkaline phosphatase is also produced by the placenta, making this an unreliable marker of liver dysfunction in pregnancy.
Authors:
Misha Moore; Catherine Nelson-Piercy
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  British journal of hospital medicine (London, England : 2005)     Volume:  72     ISSN:  1750-8460     ISO Abbreviation:  Br J Hosp Med (Lond)     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-15     Completed Date:  2011-12-23     Revised Date:  2012-03-08    
Medline Journal Info:
Nlm Unique ID:  101257109     Medline TA:  Br J Hosp Med (Lond)     Country:  England    
Other Details:
Languages:  eng     Pagination:  M170-3     Citation Subset:  IM    
Affiliation:
Obstetrics and Gynaecology, Homerton University Hospital, London.
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MeSH Terms
Descriptor/Qualifier:
Female
Humans
Liver Diseases / diagnosis*,  therapy
Liver Function Tests
Pregnancy
Pregnancy Complications / diagnosis*,  therapy
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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